Results 41 to 50 of about 889,479 (246)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Free vibration characteristics of cord-reinforced air spring with winding formation under preload conditions

AIP Advances, 2023
A precise transfer matrix was employed to analyze the free vibration characteristics of a cord-reinforced air spring with winding formation under preload conditions. The air spring was abstracted as a rotary combined shell structure with variable winding
Yu-Qiang Cheng, Lin He, Chang-Geng Shuai, Hua Gao, Jian-Guo Ma   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Adaptive Narrowband Compensation Algorithm for Active Control of the Pressure Pulsation Line Spectrum in A Liquid Pipeline System

Shock and Vibration
Active noise control technology provides a means for actively controlling pipeline pulsations. The control signal emitted by the secondary source feeds back into the reference input signal, thereby generating a pulsation coupling phenomenon.
Qichao Liu, Wenjing Yu, Guo Cheng
doaj   +1 more source

A Comparison of Finite Element Analysis (With Additional Aspects) For Predicting the Noise and Vibration for Railway Project in Malaysia

MATEC Web of Conferences, 2019
This paper is about predicting the noise and vibrations for railways project in Malaysia by using Finite Element Analysis method. In recent years, Malaysia is massively developing railways industry.
Yeo Siang Chuan, Lim Meng Hee, Eng Hoe Cheng   +2 more
doaj   +1 more source

Optimzation design of resonance changer for marine propulsion shafting in longitudinal vibration

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] The transmission path of the longitudinal vibration of propeller shafting can be changed and the base response attenuated via a Resonance Changer(RC)integrated in the thrust bearing, enabling the natural frequency of the shafting to be ...
Hu Zechao, He Lin, Xu Wei, Li Zhengmin, Zhao Xingqian   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Review of Underground Storage Tank Condition Monitoring Techniques

MATEC Web of Conferences, 2019
This article aims to provide a comprehensive review on the condition monitoring techniques of underground storage tanks (UST). Generally, the UST has long been a favourite toxic substance reservation apparatus, thanks to its large capacity and minimum ...
Ching Sheng Ooi, Ngui Wai Keng, Kar Hoou Hui, Meng Hee Lim, Leong Mohd. Salman   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source