Results 201 to 210 of about 81,538 (273)

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Correction: Steatosis is involved in the progression of kidney disease in a high-fat-diet-induced non-alcoholic steatohepatitis mouse model. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Identification of biomarkers between coronary artery disease and non-alcoholic steatohepatitis: a combination of bioinformatics and machine learning. [PDF]

Front Genet
Lin Y, Song J, Li X.
europepmc   +1 more source

Management Strategies for Refractory Esophageal Varices

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley   +1 more source

Butein Alleviates Non-Alcoholic Steatohepatitis in Leptin-Deficient Mice by Modulating the PDE4/cAMP/p-CREB Pathway. [PDF]

Drug Des Devel Ther
Guo C, Zhang Y, Xue H, Zhao X, Wang B, Deng L, Zhu X, Zhang X, Zhang Y, Liu Y.   +9 more
europepmc   +1 more source

Treatment of Hepatocellular Carcinoma Using Endoscopic Ultrasound‐guided Radiofrequency Ablation: A Case Series

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Endoscopic ultrasound‐guided radiofrequency ablation (EUS‐RFA) is an emerging technique for treating pancreatic and neuroendocrine tumors in patients who are not candidates for surgery. However, there is limited evidence of EUS‐RFA in hepatic cancers.
Yogesh Harwani, Shreya Butala, Varun Shukla, Anand Patel, Surbhi Dogra Jani   +4 more
wiley   +1 more source

Rezdiffra™ (resmetirom): a THR-β agonist for non-alcoholic steatohepatitis. [PDF]

Trends Pharmacol Sci
Brisnovali NF, Haney C, Goedeke L.
europepmc   +1 more source

Effectiveness of Gel‐immersion Endoscopic Injection Sclerotherapy Under Texture and Color Enhancement Imaging for Esophageal Varices: A Comparison of Variceal Visibility Under Gel With White Light Imaging

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objective Gel‐immersion endoscopic injection sclerotherapy (GI‐EIS) addresses the technical challenges in intravariceal injection for esophageal varices (EVs). However, gel accumulation may obscure the variceal morphology. Thus, we developed GI‐EIS under texture and color enhancement imaging (TXI) and evaluated its effectiveness.
Tsunetaka Kato, Takuto Hikichi, Jun Nakamura, Minami Hashimoto, Takumi Yanagita, Mitsuru Otsuka, Daiki Nemoto, Rei Suzuki, Mitsuru Sugimoto, Hiroyuki Asama, Kentaro Sato, Hiroshi Shimizu, Kento Osawa, Rei Ohira, Masao Kobayakawa, Hiromasa Ohira   +15 more
wiley   +1 more source

Ethanol extract of Polygonatum cyrtonema Hua mitigates non-alcoholic steatohepatitis in mice. [PDF]

Front Pharmacol
Chen D, Shen Y, Huang F, Huang B, Xu S, Li L, Liu J, Li Z, Li X.   +8 more
europepmc   +1 more source