Results 201 to 210 of about 10,125,713 (289)

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Erythritol and metabolic dysfunction‐associated steatotic liver disease: A sweet friend, bitter foe, or reliable fellow traveler?

Journal of Diabetes Investigation, EarlyView.
Kelly Hiu‐Ching Wong, David Tak‐Wai Lui, Chi‐Ho Lee   +2 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Knockdown of suppressor of glucose by autophagy (SOGA1) alleviates the progression of non-alcoholic steatohepatitis (NASH) by reducing hepatocyte senescence through regulating AMPK/mTOR-mediated mitochondrial homeostasis. [PDF]

BMC Biotechnol
Yan L, Sun H, Wang T, Chen Y, Li P.
europepmc   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

HBV reactivation and its metabolomic profile after liver transplantation for hepatocellular carcinoma in non-alcoholic steatohepatitis. [PDF]

Chin J Cancer Res
Chen J, Chen L, Li H, Hu Z, Zhuo J, Chen X, Zhao R, He C, Wu X, Lin Z, Sun J, Wang R, Wei X, Zheng S, Xu X, Lu D.   +15 more
europepmc   +1 more source

Efficiency and Safety of Endoscopic Injection Sclerotherapy With Ligation for Esophageal Varices: A Retrospective Study.

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic injection sclerotherapy (EIS) and endoscopic variceal ligation. This study aimed to compare the efficacy of conventional EIS and EISL in treating esophageal varices and the usefulness of EISL.
Keita Maki, Hiroaki Haga, Kyoko Hoshikawa, Tomohiro Katsumi, Fumiya Suzuki, Fumi Uchiyama, Yoshiyuki Ueno   +6 more
wiley   +1 more source

Quantitative longitudinal investigation of non-alcoholic steatohepatitis in mice by photoacoustic microscopy. [PDF]

Photoacoustics
Wei J, Zhang R, Jiang M, Gao L, Yu X, Liu X, Dai Y, Luo Q, Zhang Z, Yang X.   +9 more
europepmc   +1 more source

Delayed Argon Plasma Coagulation After Endoscopic Injection Sclerotherapy for Esophageal Varices Reduces Recurrence Risk

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Argon plasma coagulation (APC) is commonly used as consolidation therapy after endoscopic injection sclerotherapy (EIS) for esophageal varices (EVs); however, the optimal timing of APC remains unclear. This study evaluated the association between the EIS–APC interval and clinical outcomes.
Takumi Yanagita, Takuto Hikichi, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Mitsuru Otsuka, Eisuke Kameoka, Rei Suzuki, Mitsuru Sugimoto, Hiroyuki Asama, Hiroshi Shimizu, Kento Osawa, Rei Ohira, Keisuke Kudo, Daiki Nemoto, Masao Kobayakawa, Hiromasa Ohira   +16 more
wiley   +1 more source

Gardenia jasminoides fruit extract ameliorates non-alcoholic steatohepatitis with fibrosis by modulating inflammatory and fibrogenic pathways. [PDF]

PLoS One
Suttawong N, Witayavanitkul N, Chayanupatkul M, Wanpiyarat N, Werawatganone P, Siriviriyakul P, Werawatganon D.   +6 more
europepmc   +1 more source