Results 201 to 210 of about 71,540 (227)
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Role of non-classical monocytes in HIV-associated vascular cognitive impairment
2023ABSTRACT Despite antiretroviral treatment (cART), people living with HIV (PLWH) are more susceptible to neurocognitive impairment (NCI), probably due to synergistic/additive contribution of traditional cerebrovascular risk factors. Specifically, altered blood brain barrier (BBB) and transmigration of inflammatory monocytes are risk ...
Meera V Singh +16 more
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Transcriptomic Network Support Distinct Roles of Classical and Non-Classical Monocytes in Human
International Reviews of Immunology, 2014Classical and non-classical monocytes are two well-defined subsets of monocytes displaying distinct roles. They differentially express numerous genes relevant to their primary role. Using five independent transcriptomic microarray datasets, we ruled out several inconsistent genes and identified common genes consistently overexpressed either in ...
Christian Jörgensen +2 more
exaly +3 more sources
Non-classical monocytes have the support of the whole vascular tree
Nature Reviews Immunologyexaly +3 more sources
Non-classical monocytes in systemic lupus erythematosus (SLE)
2023Ο Συστηματικός Ερυθηματώδης Λύκος (ΣΕΛ) είναι μια χρόνια, συστημική αυτοάνοση νόσος που εκδηλώνει ποικίλες κλινικές και μοριακές διαταραχές που αποδίδονται στην απώλεια αυτοανοχής στα νουκλεϊκά οξέα και άλλα ενδογενή αντιγόνα, με συνέπεια την παραγωγή αυτοαντισωμάτων. Η υπερβολική και μη αναστρέψιμη βλάβη των ιστών που προκαλείται από τα αυτοαντισώματα
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DECREASE IN NON-CLASSICAL MONOCYTES IN MYASTHENIA GRAVIS PATIENTS
2022Circulating monocytes are mononuclear cells which are highly specialized in phagocytosis and antigen presentation, secrete a large range of different cytokines, and migrate to the tissues in response to infection and injury. Monocytes can be subdivided into three major subsets: the classical monocytes (CD14+CD16-), the intermediate monocytes (CD14+CD16+
Hemery, Edouard +6 more
openaire +4 more sources
2019
Background: Many studies suggest that circulating monocytes are actively involved in the autoimmune disease systemic sclerosis (SSc). Circulating CD14+ monocytes form a heterogeneous population and can be differentiated into classical, intermediate and non-classical monocytes, and in addition, [for full text, please go to the a.m. URL]
Friedrich, K +4 more
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Background: Many studies suggest that circulating monocytes are actively involved in the autoimmune disease systemic sclerosis (SSc). Circulating CD14+ monocytes form a heterogeneous population and can be differentiated into classical, intermediate and non-classical monocytes, and in addition, [for full text, please go to the a.m. URL]
Friedrich, K +4 more
openaire +2 more sources
Annals of the Rheumatic Diseases, 2016
Background Bone destruction in rheumatoid arthritis is mediated by osteoclasts, which are derived from precursor cells of the myeloid lineage. Although there is much known about mature osteoclasts, the identity of osteoclast precursor populations during arthritis is poorly understood.
A. Puchner +12 more
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Background Bone destruction in rheumatoid arthritis is mediated by osteoclasts, which are derived from precursor cells of the myeloid lineage. Although there is much known about mature osteoclasts, the identity of osteoclast precursor populations during arthritis is poorly understood.
A. Puchner +12 more
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341 Imiquimod-induced psoriasis requires non-classical monocytes
Journal of Investigative Dermatology, 2022Q. Chen +7 more
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Clinical and Experimental Rheumatology
Monocytes are known to be involved in both adaptive and innate immune responses, though their roles in the pathogenesis of systemic lupus erythematosus (SLE) are still unclear. Here, we performed phenotypic and functional analyses of each monocyte subset.Peripheral blood from patients with autoimmune diseases (SLE: n=53, rheumatoid arthritis: n=12 ...
Akina, Ishii +8 more
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Monocytes are known to be involved in both adaptive and innate immune responses, though their roles in the pathogenesis of systemic lupus erythematosus (SLE) are still unclear. Here, we performed phenotypic and functional analyses of each monocyte subset.Peripheral blood from patients with autoimmune diseases (SLE: n=53, rheumatoid arthritis: n=12 ...
Akina, Ishii +8 more
openaire +2 more sources
Association of elevated lipoprotein(a) level with expansion of non-classical monocytes.
Atherosclerosis, 2021A.Y. Filatova +6 more
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