Clear Cell and Non-Clear Cell Hepatocellular Carcinoma: A Case Report and Literature Review
Clear cell hepatocellular carcinoma (HCC) is an uncommon variant of HCC. It is considered to have a better prognosis than non-clear cell HCC, but recent large studies show that there is some controversy.
Jenn-Hwa Liu, Huey-Ling Tsai
doaj +5 more sources
Characteristics and Treatment Challenges of Non-Clear Cell Renal Cell Carcinoma [PDF]
Non-clear cell renal cell carcinomas (RCC) comprise several rare and poorly described diseases, often characterized by bad prognosis and with no standard treatments available. The gap in their clinical management is linked to the poor molecular characterization in handling the treatment of non clear-cell RCC with untailored therapies.
Pierangela Sepe +7 more
openaire +3 more sources
Systemic Therapy for Non–Clear Cell Renal Cell Carcinoma
Treatment options for metastatic clear cell renal cell carcinoma (ccRCC) have evolved markedly over the past decade, with multiple targeted therapies approved for the disease. In contrast, little improvement has been made in the management of metastatic non–clear cell RCC (nccRCC).
Tian, Zhang +3 more
core +5 more sources
Therapeutic approaches in clear cell and non-clear cell renal cell carcinoma
Renal cell carcinoma (RCC) accounts for 2.4% of all malignancies worldwide diagnosed with 338,000 estimated new cases globally in 2012. In the last decade, the therapeutic landscape for RCC patients has changed tremendously. In this review, we will summarize the treatment options currently available for clear-cell localized, advanced and metastatic RCC
T, Vermassen +3 more
openaire +3 more sources
Advanced Treatments in Non-Clear Renal Cell Carcinoma
PURPOSE: To focus on the use of targeted therapies against the non-clear histologic subtypes of renal cell carcinoma (RCC); papillary I and II, chromophobe, and collecting duct.
Hassan Errihani +5 more
doaj +3 more sources
Survival Outcomes Between Clear Cell and Non-Clear Cell Epithelial Ovarian Cancer [PDF]
Objective: To compare the 5-year survival rates of women with clear cell (CCC) versus those with non-clear cell (non-CCC) epithelial ovarian cancer.Materials and Methods: Retrospective study was performed on patients with epithelial ovarian cancer who ...
Wasanai Jermsirisakpong, Suphet Tuipae
doaj +1 more source
Non-Clear Cell Renal Cell Carcinoma: Current Management and Best Practice
The treatment of metastatic renal cell carcinoma (mRCC) has evolved markedly over the past several decades; first with the introduction of targeted therapies and more recently with data supporting checkpoint inhibition.
Meghan Salgia +3 more
doaj +4 more sources
Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma [PDF]
Background Nivolumab is approved for patients with metastatic renal cell carcinoma (mRCC) refractory to prior antiangiogenic therapy. The clinical activity of nivolumab in patients with non-clear cell RCC subtypes remains unknown as these patients were ...
Vadim S. Koshkin +14 more
doaj +3 more sources
Evaluation of the Relative Enhancement Ratio and Morphologic Findings on Biphasic CT to Differentiate Clear Cell and Non-Clear Cell Renal Cell Carcinoma [PDF]
Objective: To differentiate clear cell and non-clear cell renal cell carcinoma (RCC) using enhancement pattern, relative enhancement ratio and associated findings on CT scan.
Nithida Na Songkhla
doaj +3 more sources
Prognosis and Therapies in Non-Clear Cell Renal Cell Carcinomas. [PDF]
Background/Objectives: Non-clear cell renal cell carcinoma (nccRCC) comprises biologically heterogeneous renal malignancies with distinct molecular drivers, clinical behavior, and therapeutic responses. This review summarizes prognosis and systemic therapy and evaluates emerging histology-specific and biomarker-directed approaches. Methods: We analyzed
Shrivastava T +4 more
europepmc +2 more sources

