Results 21 to 30 of about 20,430,225 (174)

Genetics and Tumor Microenvironment of Renal Cell Carcinoma

Société Internationale d’Urologie Journal, 2022
Renal cell carcinoma is a diverse group of diseases that can be distinguished by distinct histopathologic and genomic features. In this comprehensive review, we highlight recent advancements in our understanding of the genetic and microenvironmental ...
Sari Khaleel, Christopher Ricketts, W. Marston Linehan, Mark Ball, Brandon Manley, Samra Turajilic, James Brugarolas, Ari Hakimi   +7 more
doaj   +1 more source

Patient Characteristics and Survival Outcomes of Non-Metastatic, Non-Clear Cell Renal Cell Carcinoma

Frontiers in Oncology, 2022
BackgroundNon-clear cell renal cell carcinoma (ccRCC) includes histologically and molecularly distinct subtypes such as papillary, chromophobe, collecting duct, and sarcomatoid RCC, with an incidence ranging from 20% to 25%.
Josiah An, Vignesh T. Packiam, Adithya Chennamadhavuni, Jordan Richards, Jayanshu Jain, Sarah L. Mott, Rohan Garje   +6 more
doaj   +1 more source

Targeted therapies for non-clear renal cell carcinoma [PDF]

Targeted Oncology, 2010
The treatment of advanced and metastatic kidney cancer has been revolutionized by the development of targeted systemic therapies. Despite the growing number of available agents approved for use against clear cell renal cell carcinoma, patients with non-clear histologies, constituting approximately 1 in 4 cases of kidney cancer, have not received the ...
Eric A, Singer, Gennady, Bratslavsky, W Marston, Linehan, Ramaprasad, Srinivasan   +3 more
openaire   +2 more sources

Clear cell renal cell carcinoma molecular variations in non‐Hispanic White and Hispanic patients

Cancer Medicine, 2023
Background The United States is becoming increasingly diverse, but few molecular studies have assessed the progression of clear cell renal cell carcinoma (ccRCC) in diverse patient populations.
Ken Batai, Yuliang Chen, Brenna A. Rheinheimer, Amit Arora, Ritu Pandey, Ronald L. Heimark, Erika R. Bracamonte, Nathan A. Ellis, Benjamin R. Lee   +8 more
doaj   +1 more source

Radiomics models based on enhanced computed tomography to distinguish clear cell from non-clear cell renal cell carcinomas

Scientific Reports, 2021
This study was to assess the effect of the predictive model for distinguishing clear cell RCC (ccRCC) from non-clear cell RCC (non-ccRCC) by establishing predictive radiomic models based on enhanced-computed tomography (CT) images of renal cell carcinoma
Ping Wang, Xu Pei, Xiao-Ping Yin, Jia-Liang Ren, Yun Wang, Lu-Yao Ma, Xiao-Guang Du, Bu-Lang Gao   +7 more
doaj   +1 more source

Non-muscle-invasive clear cell carcinoma of the urinary bladder: Is cystectomy necessary? [PDF]

, 2019
We report the clinical presentation, histological findings and management of a 49-year-old female patient with non-muscle-invasive clear cell carcinoma of the urinary bladder. In the literature, there are only seven such case reports.
Sanjeev Madaan, Tamani Jayawardhana, Hossam Alsayed, Amit Goel   +3 more
core   +1 more source

Targeted therapies and the treatment of non-clear cell renal cell carcinoma [PDF]

Annals of Oncology, 2013
Targeted therapies have shown profound effects on the outcome of patients with advanced renal cell carcinoma (RCC). However, the optimal treatment for RCC of non-clear cell histology (nccRCC)-typically excluded from trials of targeted agents-remains uncertain.By carrying out extensive searches of PubMed and ASCO databases, we identified and summarised ...
J, Bellmunt, J, Dutcher
openaire   +2 more sources

Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery [PDF]

, 2014
Background:Wider clinical applications of 9p status in clear cell renal cell carcinoma (ccRCC) are limited owing to the lack of validation and consensus for interphase fluorescent in situ hybridisation (I-FISH) scoring technique.
Fleming, S., P Rauchhaus, J Fitzpatrick, Fitzpatrick, J., N Pratt, S Fleming, J Bondad, J Cunningham, El-Mokadem, I., Cunningham, J., Bondad, J., Nabi, G., Rauchhaus, P., G Nabi, Pratt, N., I El-Mokadem   +15 more
core   +1 more source

Systematic Review of Treatment of Metastatic Non-Clear Cell Renal Cell Carcinoma

Kidney Cancer, 2022
BACKGROUND: Metastatic and unresectable non-clear cell renal cell carcinoma comprises more than a quarter of kidney cancers but does not have standardized treatment.
Jason R. Brown, Adam Calaway, Erik Castle, Jorge Garcia, Pedro C. Barata   +4 more
doaj   +1 more source

Familial non-syndromic clear cell renal cell carcinoma.

, 2004
The diagnosis of familial non-syndromic clear cell renal cell carcinoma is one of exclusion. In families presenting with clear cell RCC a germline VHL mutation and a constitutional translocation of chromosome 3 must be excluded before familial non ...
Woodward, Emma
core   +6 more sources