Results 11 to 20 of about 963,524 (371)
Human Molecular Genetics, 2006 The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a protein, but this does not mean that such RNAs do not contain information nor have function.
J. Mattick, I. Makunin
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Non‐coding RNA and cholesteatoma [PDF]
Laryngoscope Investigative Otolaryngology, 2022 AbstractObjectiveCholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master regulators orchestrating disease progression are still unknown.
Ivan Jovanovic +3 more
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Editorial: With the Eyes on Non-coding RNAs [PDF]
Frontiers in Cell and Developmental Biology, 2021 no abstract ...
Ruth Ashery-Padan +3 more
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Non coding RNA and brain [PDF]
BMC Neuroscience, 2006 Abstract Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells, with a wide spectrum of regulatory functions which include RNA modification and regulation of protein synthesis. They have been isolated and characterized in all organisms and tissues, from Archaeobacteria to mammals. In mammalian brain
PRESUTTI, Carlo +3 more
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Non-coding RNA in Neurodegeneration [PDF]
Current Geriatrics Reports, 2012 Aging-associated chronic diseases such as neurodegenerative disorders, have a dramatic impact on healthcare systems. Despite progresses in understanding their etiology, unsolved questions still exist. These complex disorders share a common inflammatory status and are influenced by common post-transcriptional mechanisms of gene regulation.
Ciccodicola A +3 more
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Non-Coding RNAs in Glioma [PDF]
Cancers, 2018 Glioma is the most aggressive brain tumor of the central nervous system. The ability of glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained proliferation, and heterogeneity contribute to an overall survival of approximately 15 months for most patients with high grade glioma.
Ryte Rynkeviciene +8 more
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Non-coding RNAs and retroviruses [PDF]
Retrovirology, 2018 Retroviruses can cause severe diseases such as cancer and acquired immunodeficiency syndrome. A unique feature in the life cycle of retroviruses is that their RNA genome is reverse transcribed into double-stranded DNA, which then integrates into the host genome to exploit the host machinery for their benefits.
Xu Zhang +4 more
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Non-Coding RNAs in Retinoblastoma [PDF]
Frontiers in Genetics, 2019 Retinoblastoma (Rb) is the most common ocular pediatric malignancy that arises from the retina and is caused by a mutation of the two alleles of the tumor suppressor gene, RB1. Although early detection provides the opportunity of controlling the primary tumor with effective therapies, metastatic activity is fatal.
Ivan Vannini, Meropi Plousiou
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Non-coding RNAs in Cardiac Regeneration [PDF]
Frontiers in Physiology, 2021 The adult heart has a limited capacity to replace or regenerate damaged cardiac tissue following severe myocardial injury. Thus, therapies facilitating the induction of cardiac regeneration holds great promise for the treatment of end-stage heart failure, and for pathologies invoking severe cardiac dysfunction as a result of cardiomyocyte death ...
Yuan, Ting, Krishnan, Jaya
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Non-Coding RNAs and Cancer [PDF]
International Journal of Molecular Sciences, 2013 The discovery of the biological relevance of non-coding RNA (ncRNAs) molecules represents one of the most significant advances in contemporary molecular biology. Expression profiling of human tumors, based on the expression of miRNAs and other short or long ncRNAs, has identified signatures associated with diagnosis, staging, progression, prognosis ...
Federica Calore +2 more
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