Results 41 to 50 of about 970,725 (346)
Microbiology Spectrum, 2023 The spread of multidrug resistant and hypervirulent Klebsiella pneumoniae has recently increased. Phages have been considered alternatives for treating infections caused by tenacious pathogens.
Huaixin Geng +7 more
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FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome
Nucleic Acids Research, 2017 Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the different classes of RNAs among the plethora of reconstructed transcripts ...
Valentin Wucher +21 more
semanticscholar +1 more source
Non‐Coding RNA Analysis Using the Rfam Database
Current Protocols in Bioinformatics, 2018 Rfam is a database of non‐coding RNA families in which each family is represented by a multiple sequence alignment, a consensus secondary structure, and a covariance model. Using a combination of manual and literature‐based curation and a custom software
Ioanna Kalvari +6 more
semanticscholar +1 more source
Non-Coding RNAs in Muscle Dystrophies [PDF]
International Journal of Molecular Sciences, 2013 ncRNAs are the most recently identified class of regulatory RNAs with vital functions in gene expression regulation and cell development. Among the variety of roles they play, their involvement in human diseases has opened new avenues of research towards the discovery and development of novel therapeutic approaches.
ERRIQUEZ, DANIELA +2 more
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Scientific Reports, 2017 Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression.
Nikolai Hecker +4 more
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The role of noncoding RNAs in cancer lipid metabolism
Frontiers in Oncology, 2022 Research on noncoding ribonucleic acids (ncRNAs) is mostly and broadly focused on microRNAs (miRNAs), cyclic RNAs (circRNAs), and long ncRNAs (lncRNAs), which have been confirmed to play important roles in tumor cell proliferation, invasion, and ...
Ye Wang +39 more
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Non-Coding RNAs and Endometrial Cancer [PDF]
Genes, 2018 Non-coding RNAs (ncRNAs) are involved in the regulation of cell metabolism and neoplastic transformation. Recent studies have tried to clarify the significance of these information carriers in the genesis and progression of various cancers and their use as biomarkers for the disease; possible targets for the inhibition of growth and invasion by the ...
Vallone C. +14 more
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CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters
Genome Biology, 2018 Background Recent experimental efforts of CRISPR-Cas9 systems have shown that off-target binding and cleavage are a concern for the system and that this is highly dependent on the selected guide RNA (gRNA) design. Computational predictions of off-targets
Ferhat Alkan +4 more
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Frontiers in Genetics, 2020 Recently, a few animals have been frequently reported to have been diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whether they are SARS-CoV-2 intermediate hosts is worthy of great attention.
Min Shen +11 more
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Non-coding RNAs in the Ovarian Follicle [PDF]
Frontiers in Genetics, 2017 The mammalian ovarian follicle is the complex reproductive unit comprising germ cell, somatic cells (Cumulus and Granulosa cells), and follicular fluid (FF): paracrine communication among the different cell types through FF ensures the development of a mature oocyte ready for fertilization.
Battaglia, Rosalia +7 more
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