Results 41 to 50 of about 867,786 (335)

Associating transcription factors and conserved RNA structures with gene regulation in the human brain

open access: yesScientific Reports, 2017
Anatomical subdivisions of the human brain can be associated with different neuronal functions. This functional diversification is reflected by differences in gene expression.
Nikolai Hecker   +4 more
doaj   +1 more source

Erratum: The Non-Coding RNA Journal Club: Highlights on Recent Papers-4. Non-Coding RNA 2016, 2, 9. [PDF]

open access: yes, 2016
Please note that in the published editorial [1], affiliations 1, and 8 contained errors.[...]
Cuerda-Gil, Diego   +9 more
core   +3 more sources

Non-Coding RNAs in Muscle Dystrophies [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
ncRNAs are the most recently identified class of regulatory RNAs with vital functions in gene expression regulation and cell development. Among the variety of roles they play, their involvement in human diseases has opened new avenues of research towards the discovery and development of novel therapeutic approaches.
ERRIQUEZ, DANIELA   +2 more
openaire   +4 more sources

miR-144/451 in hematopoiesis and beyond

open access: yesExRNA, 2019
MicroRNAs (miRNAs), a class of 18–25 nucleotide (nt) non-coding RNAs, usually inhibit the expression of their target genes. They are transcribed from endogenous genes and are processed for maturation by multiple pathways.
Ting Wang, Fan Wu, Duonan Yu
doaj   +1 more source

Predicting the Animal Susceptibility and Therapeutic Drugs to SARS-CoV-2 Based on Spike Glycoprotein Combined With ACE2

open access: yesFrontiers in Genetics, 2020
Recently, a few animals have been frequently reported to have been diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whether they are SARS-CoV-2 intermediate hosts is worthy of great attention.
Min Shen   +11 more
doaj   +1 more source

Flagella disruption in Bacillus subtilis increases amylase production yield

open access: yesMicrobial Cell Factories, 2022
Background Bacillus subtilis is a Gram-positive bacterium used as a cell factory for protein production. Over the last decades, the continued optimization of production strains has increased yields of enzymes, such as amylases, and made commercial ...
Annaleigh Ohrt Fehler   +6 more
doaj   +1 more source

Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2

open access: yesJournal of Pharmaceutical Analysis, 2021
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a serious global health threat.
Chao Liu   +5 more
doaj   +1 more source

Non-coding RNAs in the Ovarian Follicle [PDF]

open access: yesFrontiers in Genetics, 2017
The mammalian ovarian follicle is the complex reproductive unit comprising germ cell, somatic cells (Cumulus and Granulosa cells), and follicular fluid (FF): paracrine communication among the different cell types through FF ensures the development of a mature oocyte ready for fertilization.
Battaglia, Rosalia   +7 more
openaire   +4 more sources

CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters

open access: yesGenome Biology, 2018
Background Recent experimental efforts of CRISPR-Cas9 systems have shown that off-target binding and cleavage are a concern for the system and that this is highly dependent on the selected guide RNA (gRNA) design. Computational predictions of off-targets
Ferhat Alkan   +4 more
doaj   +1 more source

The non-coding RNA landscape of plasma cell dyscrasias [PDF]

open access: yes, 2020
Despite substantial advancements have been done in the understanding of the pathogenesis of plasma cell (PC) disorders, these malignancies remain hard-to-treat.
Azab, Kareem A   +3 more
core   +1 more source

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