Results 41 to 50 of about 39,020 (125)
Interplay between single-stranded binding proteins on RNA secondary structure [PDF]
Phys. Rev. E 88, 052707 (2013), 2013 RNA protein interactions control the fate of cellular RNAs and play an important role in gene regulation. An interdependency between such interactions allows for the implementation of logic functions in gene regulation. We investigate the interplay between RNA binding partners in the context of the statistical physics of RNA secondary structure, and ...
arxiv +1 more source
Frontiers in Microbiology, 2015 Carbapenem-resistant Acinetobacter baumannii (CRAB) presents a serious therapeutic and infection control challenge. In this study, we investigated the epidemiological and molecular differences of CRAB, and the threatening factors for contributing to ...
Yaowen eChang +10 more
doaj +1 more source
Shapes of interacting RNA complexes [PDF]
arXiv, 2014 Shapes of interacting RNA complexes are studied using a filtration via their topological genus. A shape of an RNA complex is obtained by (iteratively) collapsing stacks and eliminating hairpin loops. This shape-projection preserves the topological core of the RNA complex and for fixed topological genus there are only finitely many such shapes.Our main ...
arxiv
Quality Assessment of Domesticated Animal Genome Assemblies
Bioinformatics and Biology Insights, 2015 The era of high-throughput sequencing has made it relatively simple to sequence genomes and transcriptomes of individuals from many species. In order to analyze the resulting sequencing data, high-quality reference genome assemblies are required. However,
Stefan E. Seemann +3 more
doaj +1 more source
Gut Pathogens, 2018 Background Diarrheagenic Escherichia coli (DEC) is one of the most important etiological agents of diarrheal diseases. In this study we investigated the prevalence, virulence gene profiles, antimicrobial resistance, and molecular genetic characteristics ...
Dan Li +8 more
doaj +1 more source
Can we always sweep the details of RNA-processing under the carpet? [PDF]
, 2013 RNA molecules follow a succession of enzyme-mediated processing steps from transcription until maturation. The participating enzymes, for example the spliceosome for mRNAs and Drosha and Dicer for microRNAs, are also produced in the cell and their copy-numbers fluctuate over time.
arxiv +1 more source
LncRNAs SOX2-OT and NEAT1 act as a potential biomarker for esophageal squamous cell carcinoma
Discover OncologyDespite strides in diagnostic and therapeutic approaches for ESCC, patient survival rates remain relatively low. Recent studies highlight the pivotal role of long non-coding RNAs (lncRNAs) in regulating diverse cellular activities in humans. Dysregulated
Rajiv Ranjan Kumar +5 more
doaj +1 more source
Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2
Journal of Pharmaceutical Analysis, 2021 The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a serious global health threat.
Chao Liu +5 more
doaj
Combinatorics Of RNA Structures With Pseudoknots [PDF]
arXiv, 2007 In this paper we derive the generating function of RNA structures with pseudoknots. We enumerate all $k$-noncrossing RNA pseudoknot structures categorized by their maximal sets of mutually intersecting arcs. In addition we enumerate pseudoknot structures over circular RNA. For 3-noncrossing RNA structures and RNA secondary structures we present a novel
arxiv
3D RNA and functional interactions from evolutionary couplings [PDF]
arXiv, 2015 Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces research on their structure and functional interactions. We mine the evolutionary sequence record to derive precise information about function and structure of RNAs and RNA-protein complexes.
arxiv