Results 41 to 50 of about 863,687 (283)
miR-144/451 in hematopoiesis and beyond
ExRNA, 2019 MicroRNAs (miRNAs), a class of 18–25 nucleotide (nt) non-coding RNAs, usually inhibit the expression of their target genes. They are transcribed from endogenous genes and are processed for maturation by multiple pathways.
Ting Wang, Fan Wu, Duonan Yu
doaj +1 more source
The role of noncoding RNAs in cancer lipid metabolism
Frontiers in Oncology, 2022 Research on noncoding ribonucleic acids (ncRNAs) is mostly and broadly focused on microRNAs (miRNAs), cyclic RNAs (circRNAs), and long ncRNAs (lncRNAs), which have been confirmed to play important roles in tumor cell proliferation, invasion, and ...
Ye Wang +39 more
doaj +1 more source
Non-Coding RNAs in Retinoblastoma [PDF]
Frontiers in Genetics, 2019 Retinoblastoma (Rb) is the most common ocular pediatric malignancy that arises from the retina and is caused by a mutation of the two alleles of the tumor suppressor gene, RB1. Although early detection provides the opportunity of controlling the primary tumor with effective therapies, metastatic activity is fatal.
Meropi Plousiou, Ivan Vannini
openaire +3 more sources
The non-coding RNA landscape of plasma cell dyscrasias [PDF]
, 2020 Despite substantial advancements have been done in the understanding of the pathogenesis of plasma cell (PC) disorders, these malignancies remain hard-to-treat.
Azab, Kareem A +3 more
core +1 more source
CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters
Genome Biology, 2018 Background Recent experimental efforts of CRISPR-Cas9 systems have shown that off-target binding and cleavage are a concern for the system and that this is highly dependent on the selected guide RNA (gRNA) design. Computational predictions of off-targets
Ferhat Alkan +4 more
doaj +1 more source
Frontiers in Genetics, 2020 Recently, a few animals have been frequently reported to have been diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whether they are SARS-CoV-2 intermediate hosts is worthy of great attention.
Min Shen +11 more
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Flagella disruption in Bacillus subtilis increases amylase production yield
Microbial Cell Factories, 2022 Background Bacillus subtilis is a Gram-positive bacterium used as a cell factory for protein production. Over the last decades, the continued optimization of production strains has increased yields of enzymes, such as amylases, and made commercial ...
Annaleigh Ohrt Fehler +6 more
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Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]
, 2020 Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G. +9 more
core +1 more source
Non-coding RNAs and retroviruses [PDF]
Retrovirology, 2018 Retroviruses can cause severe diseases such as cancer and acquired immunodeficiency syndrome. A unique feature in the life cycle of retroviruses is that their RNA genome is reverse transcribed into double-stranded DNA, which then integrates into the host genome to exploit the host machinery for their benefits.
Xu Zhang +4 more
openaire +3 more sources
Potential treatment with Chinese and Western medicine targeting NSP14 of SARS-CoV-2
Journal of Pharmaceutical Analysis, 2021 The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a serious global health threat.
Chao Liu +5 more
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