Results 51 to 60 of about 39,020 (125)
Emerging applications of read profiles towards the functional annotation of the genome
Frontiers in Genetics, 2015 Functional annotation of the genome in various species is important to understand their phenotypic complexity. The road towards functional annotation involves several challenges ranging from experiments on individual molecules to large-scale analysis of ...
Sachin ePundhir +2 more
doaj +1 more source
A Panel of Synapse-Related Genes as a Biomarker for Gliomas
Frontiers in Neuroscience, 2020 Gliomas are the most common primary brain cancers. In recent years, IDH mutation and 1p/19q codeletion have been suggested as biomarkers for the diagnosis, treatment, and prognosis of gliomas.
Xiangwen Ji +4 more
doaj +1 more source
Prediction of RNA pseudoknots by Monte Carlo simulations [PDF]
arXiv, 2004 In this paper we consider the problem of RNA folding with pseudoknots. We use a graphical representation in which the secondary structures are described by planar diagrams. Pseudoknots are identified as non-planar diagrams. We analyze the non-planar topologies of RNA structures and propose a classification of RNA pseudoknots according to the minimal ...
arxiv
RNA sampling and crystallographic refinement using Rappertk [PDF]
arXiv, 2007 Background. Dramatic increases in RNA structural data have made it possible to recognize its conformational preferences much better than a decade ago. This has created an opportunity to use discrete restraint-based conformational sampling for modelling RNA and automating its crystallographic refinement. Results.
arxiv
An observation of circular RNAs in bacterial RNA-seq data [PDF]
arXiv, 2016 Circular RNAs (circRNAs) are a class of RNA with an important role in micro RNA (miRNA) regulation recently discovered in Human and various other eukaryotes as well as in archaea. Here, we have analyzed RNA-seq data obtained from {\it Enterococcus faecalis} and {\it Escherichia coli} in a way similar to previous studies performed on eukaryotes.
arxiv
Cell Death and Diseaseβ-Hydroxybutyrate (β-OHB), the primary ketone body, is a bioactive metabolite that acts as both an energy substrate and a signaling molecule. Recent studies found that β-OHB inhibits the production of pro-inflammatory cytokines in macrophages, but its ...
Ya-Ping Bai +14 more
doaj +1 more source
RNA-GPT: Multimodal Generative System for RNA Sequence Understanding [PDF]
arXivRNAs are essential molecules that carry genetic information vital for life, with profound implications for drug development and biotechnology. Despite this importance, RNA research is often hindered by the vast literature available on the topic. To streamline this process, we introduce RNA-GPT, a multi-modal RNA chat model designed to simplify RNA ...
arxiv
enod40, a gene expressed during nodule organogenesis, codes for a non-translatable RNA involved in plant growth. [PDF]
, 1994 Martín Crespi +6 more
openalex +1 more source
On an RNA-membrane protogenome [PDF]
arXivSelected ribonucleotide sequences bind well to zwitterionic phospholipid bilayer membranes, though randomized RNAs do not. There are no evident repeated sequences in selected membrane binding RNAs. This implies small and varied motifs responsible for membrane affinity. Such subsequences have been partially defined. Bound RNAs require divalents like Mg2+
arxiv