Results 51 to 60 of about 970,725 (346)
Advances in Non-Coding RNA Sequencing [PDF]
Non-Coding RNA, 2021 Non-coding RNAs (ncRNAs) comprise a set of abundant and functionally diverse RNA molecules. Since the discovery of the first ncRNA in the 1960s, ncRNAs have been shown to be involved in nearly all steps of the central dogma of molecular biology. In recent years, the pace of discovery of novel ncRNAs and their cellular roles has been greatly accelerated
Julia Micheel +2 more
openaire +4 more sources
miR-144/451 in hematopoiesis and beyond
ExRNA, 2019 MicroRNAs (miRNAs), a class of 18–25 nucleotide (nt) non-coding RNAs, usually inhibit the expression of their target genes. They are transcribed from endogenous genes and are processed for maturation by multiple pathways.
Ting Wang, Fan Wu, Duonan Yu
doaj +1 more source
Flagella disruption in Bacillus subtilis increases amylase production yield
Microbial Cell Factories, 2022 Background Bacillus subtilis is a Gram-positive bacterium used as a cell factory for protein production. Over the last decades, the continued optimization of production strains has increased yields of enzymes, such as amylases, and made commercial ...
Annaleigh Ohrt Fehler +6 more
doaj +1 more source
Molecular Cancer, 2019 The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an oncogenic regulator of several cancers. However, its expression and function in gallbladder cancer (GBC) remain largely unknown.
Jianan Chen +13 more
semanticscholar +1 more source
Non-Coding RNAs in Hodgkin Lymphoma [PDF]
International Journal of Molecular Sciences, 2017 MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression by binding to the 3’-UTR of their target genes, can act as oncogenes or tumor suppressors. Recently, other types of non-coding RNAs—piwiRNAs and long non-coding RNAs—have also been identified. Hodgkin lymphoma (HL) is a B cell origin disease characterized by the presence of only 1%
Anna Cordeiro +2 more
openaire +4 more sources
Long Non-Coding RNA in the Pathogenesis of Cancers
Cells, 2019 The incidence and mortality rate of cancer has been quickly increasing in the past decades. At present, cancer has become the leading cause of death worldwide. Most of the cancers cannot be effectively diagnosed at the early stage.
Yujing Chi +4 more
semanticscholar +1 more source
LncRNADisease 2.0: an updated database of long non-coding RNA-associated diseases
Nucleic Acids Res., 2018 Mounting evidence suggested that dysfunction of long non-coding RNAs (lncRNAs) is involved in a wide variety of diseases. A knowledgebase with systematic collection and curation of lncRNA-disease associations is critically important for further examining
Zhenyu Bao +5 more
semanticscholar +1 more source
Frontiers in Microbiology, 2021 Hypervirulent Klebsiella pneumoniae (hvKp), one of the major community-acquired pathogens, can cause invasive infections such as liver abscess. In recent years, bacteriophages have been used in the treatment of K.
Lingjie Song +8 more
doaj +1 more source
Non-coding RNA regulatory networks. [PDF]
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 It is well established that the vast majority of human RNA transcripts do not encode for proteins and that non-coding RNAs regulate cell physiology and shape cellular functions. A subset of them is involved in gene regulation at different levels, from epigenetic gene silencing to post-transcriptional regulation of mRNA stability.
S. Panni +3 more
semanticscholar +5 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source