Results 61 to 70 of about 39,020 (125)
Identification and Analysis of Arabidopsis Expressed Sequence Tags Characteristic of Non-Coding RNAs [PDF]
, 2001 Gustavo C. MacIntosh +2 more
openalex +1 more source
International Journal of Genomics, 2017 miR-28-5p is an intragenic miRNA which is underexpressed in several tumor types showing a tumor suppressor (TS) activity. Routinely, the known miR-28-5p targets are validated in specific tumor contexts but it is unclear whether these targets are also ...
Milena Rizzo +5 more
doaj +1 more source
How Large is the Universe of RNA-Like Motifs? A Clustering Analysis of RNA Graph Motifs Using Topological Descriptors [PDF]
arXivWe introduce a computational topology-based approach with unsupervised machine-learning algorithms to estimate the database size and content of RNA-like graph topologies. Specifically, we apply graph theory enumeration to generate all 110,667 possible 2D dual graphs for vertex numbers ranging from 2 to 9.
arxiv
Non‐coding RNAs: the architects of eukaryotic complexity [PDF]
, 2001 John S. Mattick
openalex +1 more source
The miRNA and PD-1/PD-L1 signaling axis: an arsenal of immunotherapeutic targets against lung cancer
Cell Death DiscoveryLung cancer is a severe challenge to the health care system with intrinsic resistance to first and second-line chemo/radiotherapies. In view of the sterile environment of lung cancer, several immunotherapeutic drugs including nivolumab, pembrolizumab ...
Ritu Yadav +17 more
doaj +1 more source
iScience, 2022 Summary: GINS1 is a GINS complex subunit that functions along with the MCM2-7 complex and Cdc45 in eukaryotic DNA replication. Despite the significance of the GINS complex in the switch between quiescence and proliferation of glioma cells inside and ...
Hui Yang +6 more
doaj
Beyond the proteome: non-coding regulatory RNAs. [PDF]
, 2002 M. Szymański, Jan Barciszewski
openalex +1 more source
DiseasesPancreatic (PC), colorectal (CRC), hepatocellular (HCC), and gallbladder (GC) cancers together account for nearly 20% of all cancer cases. However, specific biomarkers and therapeutic targets for these cancers are lacking.
Sanjana Bana +10 more
doaj +1 more source
Parametric analysis of RNA folding [PDF]
arXiv, 2009 We extend recent methods for parametric sequence alignment to the parameter space for scoring RNA folds. This involves the construction of an RNA polytope. A vertex of this polytope corresponds to RNA secondary structures with common branching. We use this polytope and its normal fan to study the effect of varying three parameters in the free energy ...
arxiv