Results 31 to 40 of about 60,516 (300)

Plasma free fatty acid levels influence Zn2+-dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin [PDF]

, 2014
Background: Histidine-rich glycoprotein (HRG) regulates coagulation, through its ability to bind and neutralize heparins. HRG associates with zinc ions (Zn2+) to stimulate HRG-heparin complex formation. Under normal conditions the majority of plasma Zn2+
Schwarz-Linek, Ulrich, Blindauer, Claudia A, Stewart, Alan J., Blindauer, Claudia A., Kassaar, Omar   +4 more
core   +1 more source

THE EFFECT OF EXERCISE ON THE LEVEL OF NON‐ESTERIFIED FATTY ACIDS IN THE BLOOD [PDF]

Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1960
During a period of one hour's moderate exercise, walking on a treadmill, in the post‐absorptive state, the mean concentration of non‐esterified fatty acids (NEFA) in ten healthy subjects rose from 0–76 to 1–44 m‐mole/ l. This observation is consistent with the view that fat is transported as NEFA from adiposetissue to muscle, as a fuel for exercise. In
A, BASU, R, PASSMORE, J A, STRONG
openaire   +2 more sources

NEFAs Influence the Inflammatory and Insulin Signaling Pathways Through TLR4 in Primary Calf Hepatocytes in vitro

Frontiers in Veterinary Science, 2021
Transition dairy cows are often in a state of negative energy balance because of decreased dry matter intake and increased energy requirements, initiating lipid mobilization and leading to high serum β-hydroxybutyrate (BHBA) and non-esterified fatty acid
Qinghua Deng, Qinghua Deng, Liyin Du, Liyin Du, Yuming Zhang, Yuming Zhang, Guowen Liu, Guowen Liu   +7 more
doaj   +1 more source

Analytical methods in dairy cows nutrition and their application in creation of production health

Acta Fytotechnica et Zootechnica, 2016
The effect of quantity of nutrients on rumen fermentation and the level of metabolic markers in blood serum were simultaneously analysed in groups of dairy cows 21 days before and 21 days after parturition with aim to diagnose disorders in milk ...
Vladimír Vajda, Iveta Maskaľová, Lukáš Bujňák   +2 more
doaj   +1 more source

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

, 2012
Nutrition during development affects risk of future cardiovascular disease. Relatively little is known about whether the amount and type of fat in the maternal diet affect vascular function in the offspring.
Masoodi, Mojgan, Geraldine F Clough, Karen A Lillycrop, Samuel P Hoile, Karen A. Lillycrop, Irvine, Nicola A., Philip C. Calder, Graham C. Burdge, Kelsall, Christopher J., Christopher Torrens (114420), Geraldine F. Clough, Geraldine F. Clough (114433), Christopher J. Kelsall, Lillycrop, Karen A., Calder, Philip C., Mojgan Masoodi (152735), Mark A. Hanson (114427), Hoile, Samuel P., Burdge, Graham C., Christopher J. Kelsall (173702), Mark A Hanson, Christopher J Kelsall, Graham C Burdge, Nicola A. Irvine (173711), Torrens, Christopher, Samuel P. Hoile, Nicola A Irvine, Graham C. Burdge (173729), Philip C Calder, Mojgan Masoodi, Hanson, Mark A., Philip C. Calder (173723), Christopher Torrens, Nicola A. Irvine, Clough, Geraldine F., Mark A. Hanson, Samuel P. Hoile (173705), Karen A. Lillycrop (173718)   +37 more
core   +1 more source

Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR γ to suppress colitis. [PDF]

, 2012
Inflammatory bowel disease (IBD) therapies are modestly successful and associated with significant side effects. Thus, the investigation of novel approaches to prevent colitis is important.
Vogel, Hans, Christian Jobin (74703), Adria Carbo, Mireia Pedragosa, Jobin, Christian, Christian Jobin, Monica Viladomiu (120075), Carbo, Adria, Mireia Pedragosa (120080), Janelle C Arthur, Martin Storr (124415), Hans Vogel (182237), Benjamin A. Corl (182236), Hans Vogel, Viladomiu, Monica, Adria Carbo (120066), Arthur, Janelle C., Shaykhutdinov, Rustem, Pedragosa, Mireia, Storr, Martin, Raquel Hontecillas (120113), Bassaganya-Riera, Josep, De Simone, Claudio, Janelle C. Arthur (143340), Claudio De Simone (171437), Monica Viladomiu, Rustem Shaykhutdinov (182227), Rustem Shaykhutdinov, Martin Storr, Claudio De Simone, Josep Bassaganya-Riera (120051), Hontecillas, Raquel, Benjamin A Corl, Josep Bassaganya-Riera, Corl, Benjamin A., Raquel Hontecillas   +35 more
core   +1 more source

Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy. [PDF]

PLoS ONE, 2015
Pregnancy is characterized by a complexity of metabolic processes that may impact fetal development and ultimately, infant health outcomes. However, our understanding of whole body maternal and fetal metabolism during this critical life stage remains ...
Karen L Lindsay, Christian Hellmuth, Olaf Uhl, Claudia Buss, Pathik D Wadhwa, Berthold Koletzko, Sonja Entringer   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Considerations about the in situ derivatization and fractionation of EFA and NEFA in biological and food samples

MethodsX, 2015
Despite their important role in tissues, fluids and foods, the analysis of non-esterified fatty acids (NEFA) as methyl esters (NEFAME) is performed using expensive, cumbersome and time-consuming procedures that needs of isolation, fractionation and ...
Lígia L. Pimentel, Ana L. Fontes, Ana M. Gomes, Luis M. Rodríguez-Alcalá   +3 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source