Results 61 to 70 of about 58,526 (293)

Allosteric modulation of zinc speciation by fatty acids [PDF]

Background: Serum albumin is the major protein component of blood plasma and is responsible for the circulatory transport of a range of small molecules that include fatty acids, hormones, metal ions and drugs.
Sadler, P. J., Stewart, Alan J. S., Blindauer, Claudia A., Barnett, James P., Dr., Martin, Esther M., Khazaipoul, Siavash, Kassaar, Omar   +6 more
core   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Effect of Intravenous Amino Acids on Plasma Non-Esterified Fatty Acids.

Experimental Biology and Medicine, 1959
Summary(1) The effect of infusing an amino acid mixture (protein hydrolysate) on plasma NEFA, venous glucose level, and capillary-venous glucose difference, was studied in 6 healthy volunteer subjects. In every instance, plasma NEFA levels fell precipitously during amino acid infusion, and capillary-venous glucose differences increased concurrently ...
S A, HASHIM, T B, VAN ITALLIE
openaire   +2 more sources

Intensity of transition of heavy metals and content of non-esterified forms of fatty acids in newly constructed bee combs

Біологічні студії
Background. There is a debate in the literature about the presence of heavy metals, including toxic ones, in freshly built bee combs (tongues). At the same time, heavy metals in the wax-synthesizing glands of bees are involved in the synthesis of various
Yosyp Rіvіs, Volodymyr Pоstоienkо, Оlha Hоpаnеnkо, Ulyana Fedorovych, Daniel Zaborski, Оlha Stаdnytskа, Іvan Sаrаnchuk, Оleh Klym, Аndrii Shеlеvаch, Оleksandr Diachеnkо, Olena Bezaltychna   +10 more
doaj   +1 more source

Effect of Non-Esterified Fatty Acids on Fatty Acid Metabolism-Related Genes in Calf Hepatocytes Cultured in Vitro

Cellular Physiology and Biochemistry, 2013
Background: NEFA plays numerous roles in the metabolism of glucose, lipids, and proteins. A number of experimental studies have shown that NEFA may have an important role in fatty acid metabolism in the liver, especially in dairy cows that experience ...
Peng Li, Yiming Liu, Yi Zhang, Miao Long, Yang Guo, Zhe Wang, Xinwei Li, Cai Zhang, Xiaobing Li, Jianbin He, Guowen Liu   +10 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Circulating non-esterified fatty acids in the lean and obese subjects (left two columns), and in three subjects whose non-esterified fatty acids extracted for tissue culture experiments (right three columns).

, 2016
Circulating non-esterified fatty acids in the lean and obese subjects (left two columns), and in three subjects whose non-esterified fatty acids extracted for tissue culture experiments (right three columns).
Latoya E. Campbell (2939922), Lori R. Roust (2993127), Lawrence J. Mandarino (201367), Chad C. Carroll (703759), Elena De Filippis (2993133), Dawn K. Coletta (251343), Douglas F. Lake (2347042), Christos S. Katsanos (201385), Lee Tran (2106961), Paul D. Hanavan (2993130)   +9 more
core   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Flexible Biofoams Based on Furanics and Fatty Acids Esterified Tannin

, 2023
Water repellant, flexible biofoams using tannin esterified with various fatty acid chains, namely lauric, palmitic and oleic acids, by reaction with lauryl chloride, palmitoyl chloride, and oleyl chloride were developed and their characteristics compared
Ummi Hani Abdullah, Antonio Pizzi, Azadeh, Elham, Abdullah, Ummi Hani, Pizzi, Antonio, Gerardin, Philippe, Cesar Segovia, Gerardin, Christine, Elham Azadeh, Christine Gerardin, Philippe Gerardin, Segovia, Cesar   +11 more
core   +1 more source