Results 81 to 90 of about 30,049 (242)

Effects of food restriction on serum concentration of glucose, triacylglycerol, beta-hydroxy butyrate, non-esterified fatty acids and urea in pregnant ewes [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2011
Food restriction is a potential unwanted risk for a developing fetus in pregnant ewe. The objective of this study was to study the effects of food restriction on serum concentration of glucose, triacylglycerol, non-esterified fatty acids, beta ...
A Rezapour, M Taghinezhad, GH.R Assadnasab   +2 more
doaj  

Chemiluminescecnt determination of serum non-esterified fatty acids.

BUNSEKI KAGAKU, 1988
We have developed a method for chemiluminescent determination of serum non-esterified fatty acids (NEFA) using acyl-CoA synthetase, acyl-CoA oxidase, iso-luminol and micro peroxidase. Since the determination of serum NEFA by the chemiluminescence method was interfered with serum bilirubin, the bilirubin oxidase was used to eliminate the effect of ...
Yosinori UJI, Yoshi SAKAI, Masataka SHIRAKI, Akio NOMA, Masako MAEDA, Akio TSUJI, Hiroaki OKABE   +6 more
openaire   +2 more sources

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

STUDIES ON NON ESTERIFIED FATTY ACID LEVELS IN ORTHOSTIC HYPOTENSION

Nihon Naika Gakkai Zasshi, 1972
起立性低血圧の病態を血漿遊離脂肪酸(NEFA)の面から検討する目的でtilting60°による体位変換を行ない,正常血圧者および各種疾患と対比した.さらに各種起立性低血圧(高血圧性,脳血管性,糖尿病性,特発性)についても検討を行なつた.正常血圧者では, tiltingによりNEFAの上昇がみられたが,起立性低血圧ではtiltingによる交感神経系の反応が欠如し, hypotone型に比し, hypodyname型にNEFAの上昇抑制が著しく,起立による血圧下降の程度とNEFAの上昇抑制とは平行関係が認められた.疾患別では特発性のものでNEFAの抑制が最も強く,糖尿病性においては軽度であつた.さらに人為的に起立性血圧下降を惹起させると,起立性低血圧と同様なNEFAの反応を示した.治療薬として ...
openaire   +2 more sources

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

The determinants of fasting and post-load non-esterified fatty acids in older adults: The cardiovascular health study. [PDF]

Metabol Open, 2023
Bene-Alhasan Y, Siscovick DS, Ix JH, Kizer JR, Tracy R, Djoussé L, Mukamal KJ.   +6 more
europepmc   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Changes in Body Reserves, Non-Esterified Fatty Acids, and Leptin during the Reproductive Lifespan of the Rabbit Female. [PDF]

Animals (Basel), 2023
Peiró R, Argente MJ, García ML.
europepmc   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source