Results 81 to 90 of about 61,302 (299)

Plasma fatty acids and [13C]linoleic acid metabolism in preterm infants fed a formula with medium-chain triglycerides

open access: yesJournal of Lipid Research, 2003
Most preterm infant formulas contain medium-chain triacylglycerols (M80), but the effects of MCT on polyunsaturated fatty acid status and metabolism are controversial. Thus, we studied the effects of MCT on linoleic acid metabolism using stable isotopes.
Maria Rodriguez   +6 more
doaj   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

open access: yes, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

The Possible Role of 3-lodothyronamine in Browning of Inguinal White Adipose Tissue in Mice

open access: yesEndocrinology Research and Practice, 2017
Purpose: In this study, we have investigated whether administration of a chronic low dose of 3-iodothyronamine (T1AM) could regulate the concentration of uncoupling protein 1 (UCP1) in mice inguinal white adipose tissue (IWAT).
Neda ESKANDARZADE   +3 more
doaj   +1 more source

Studies relating to Polyunsaturated Fatty Acid (PUFA) Supplementation and Fertility in Cattle [PDF]

open access: yes, 2007
End of project reportReproductive inefficiency has a significant impact on the economic performance of both dairy and beef herds, particularly in seasonal calving systems. Nutrition plays a fundamental role in reproduction. Furthermore, there is emerging
Childs, Stuart   +3 more
core  

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu   +12 more
wiley   +1 more source

Association between plasma metabolites and gene expression profiles in five porcine endocrine tissues

open access: yesGenetics Selection Evolution, 2011
Background Endocrine tissues play a fundamental role in maintaining homeostasis of plasma metabolites such as non-esterified fatty acids and glucose, the levels of which reflect the energy balance or the health status of animals.
Bassols Anna   +3 more
doaj   +1 more source

Pioglitazone increases non-esterified fatty acid clearance in upper body obesity [PDF]

open access: yesDiabetologia, 2005
Plasma NEFA concentrations are largely determined by adipose tissue lipolysis. Insulin suppression of lipolysis is commonly impaired with insulin resistance and improves with thiazolidinedione treatment of type 2 diabetes. The present studies were designed to assess the effects of thiazolidinedione on NEFA (oleate) metabolism that are independent of ...
S, Shadid, M D, Jensen
openaire   +2 more sources

Characterization of milk fatty acids based on genetic and herd parameters [PDF]

open access: yes, 2012
The objective of this study was to characterize the fatty acids (FA) in milk based on genetic and herd parameters to investigate the origin of the different FA in milk.
Bovenhuis, H.   +4 more
core   +2 more sources

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

open access: yesAdvanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao   +16 more
wiley   +1 more source

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