Results 61 to 70 of about 534,262 (294)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Organizational Culture and Self-Efficacy with Work Motivation and Leadership as Key Factors
Qubahan Academic JournalTo examine these relationships in a school setting, this study investigates the effects of organizational culture on teacher performance directly using leadership and work motivation as mediators and ‘self-efficacy’ variables.
Wahyul Huda +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
EDUCAŢIA DE GEN ÎN CONTEXT FORMAL-NONFORMAL-INFORMAL
Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2021 În prezentul articol este abordată educația de gen. Constatările și concluziile sunt făcute în baza analizei unor experiențe practice, subiectul fiind explorat în context formal-nonformal-informal.
Valentina BODRUG-LUNGU
doaj
Social networks as a tool of non-formal education in the training of teachers of vocational training
, 2022 Ірина Каменська +1 more
openalex +2 more sources
Professional identity and competences of adult learning facilitators: Perspectives from Mongolian non-formal adult education [PDF]
, 2021 Togtokhmaa Zagir
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Aesthetic Hybridization in the Creation of Contemporary Batik Motif Design
Open Cultural StudiesThe development of contemporary Semarang batik as an expression of personal expression free from the boundaries of traditional rules is feared to threaten the existence of traditional batik.
Syakir Syakir +6 more
doaj +1 more source
"FORMAL" AND "NON-FORMAL" EDUCATION IN THE DIFFERENTIATION OF INTRINSIC PROPERTIES
Освітній дискурс, 2019 The article analyzes the definitions of "formal" and "non- formal" education as varieties of lifelong learning in the context of foreign and Ukrainian scholars. The meaningful field of "lifelong education" in the coordinates of interdisciplinary research
Volodymyr Slabko +2 more
doaj +1 more source