Results 71 to 80 of about 2,541,010 (310)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Lifelong learning inequality? The relevance of family background for on-the-job training [PDF]
"Despite ample evidence on intergenerational persistence of formal education as well as on the determinants of non-formal training, these issues have not yet been analysed jointly. The question remains whether people from low-qualified family backgrounds
Antoni, Manfred
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Life Long Education: A Conceptual Debate
Seminar.net, 2009 This paper deals with the nature of a concept of lifelong education. Lifelong education can be provided through informal, formal and non-formal education processes.
Muhammad Javed Iqbal
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Discover Global SocietyWest Bengal in India is one of the worst impacted states by the cyclones. The first super cyclone after the 1999 super cyclone was in May 2020, called cyclone Amphan, which devastated West Bengal to its core, especially the North 24 Parganas and South 24
Tisha Goswami, Zafar Tabrez
doaj +1 more source
Non Formal Education in the Prevention of Alcohol-related Problems
Saber & Educar, 2014 The consumption of alcohol by young people and alcohol problems have been a growing concern in Portugal and worldwide. The origin of these consumptions arise numerous reasons, among them, the frustration of basic psychological needs (NPB), situation ripe
Tatiana Nunes +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
PERILAKU SOSIAL PEMAIN SEPAKBOLA BERDASARKAN LATAR BELAKANG PENDIDIKAN :Studi Deskriptif pada Sekolah Sepakbola di Kota Bandung [PDF]
, 2015 Tujuan penelitian ini untuk: 1) Mengetahui bagaimana perilaku sosial pemain sepakbola yang berdasarkan hanya pada latar belakang pendidikan formal (Sekolah dasar) saja?
Iqbal, Herdy Sopyan
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