Results 51 to 60 of about 1,589,731 (349)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Climate change and sustainability: a critical analysis of Indian curriculum

Discover Education
Environmental education is increasingly recognized as a critical component in fostering sustainable thinking and climate resilience among students. In India, educational policy has progressively evolved to embed climate change and sustainability across ...
Meenakshi Singh, Ansar Ahmad
doaj   +1 more source

Leadership Styles and Remote Work Dynamics

Education Sciences
Background: The COVID-19 pandemic uniquely challenged non-formal education (NFE), a sector reliant on interpersonal engagement, by forcing a rapid shift to remote work.
Asmahan Masry-Herzallah, Hanan Sarhan, Zehavit Gross   +2 more
doaj   +1 more source

Learning process for creating community identity

SHS Web of Conferences, 2016
Creating community identity needs a learning process to assist community to identify, recognize, build acceptance and cultivate awareness in identity. The purpose of this study was to develop the draft of a learning process to create community identity ...
Ratanakosol Kulthida, Pathumcharoenwattana Wiratep, Kimpee Pan   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Participatory-based management of village-owned enterprises to optimize village original revenue: A case study of Tridadi Makmur, Sleman, Indonesia

Journal of Community Service and Empowerment
Village-owned enterprises have been positioned as strategic instruments for strengthening local economic autonomy, yet many village enterprises in Indonesia still struggle to contribute meaningfully to village original revenue.
M. Murtodo, Puji Yanti Fauziah
doaj   +1 more source

IMPROVING EARLY CHILDHOOD COGNITIVE ABILITIES THROUGH HAND MOVEMENT METHOD

Empowerment, 2021
The purpose of this study was to examine how early childhood cognitive ability development occurs in case 1) Memory 2) Recognize numbers and their sequences, and 3) Application of educational materials in everyday life.
Ratna Lina Marliana, Nandang Rukanda, Sri Nurhayati   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Analysis of Non-formal Education (NFE) Needs in Schools

Journal of Nonformal Education, 2020
The research objective is to determine the role of Non-formal Education (NFE) programs in schools and children’s interest in Non-formal Education The study uses a quantitative analysis approach.
Widodo Widodo, Widya Nusantara
semanticscholar   +2 more sources

Implementing independent workforce training to strengthen community empowerment: Evidence from PKBM Wijaya Kusuma, Yogyakarta

Journal of Community Service and Empowerment
Urban unemployment remains a persistent challenge in Yogyakarta, particularly for people of productive age who have limited access to formal employment and market-relevant skills.
Dyah Maydhaningrum, Puji Yanti Fauziah
doaj   +1 more source