Results 61 to 70 of about 237,923 (376)

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

An Open Resource for Non-human Primate Imaging [PDF]

open access: yes, 2018
Non-human primate neuroimaging is a rapidly growing area of research that promises to transform and scale translational and cross-species comparative neuroscience.
Milham, Michael P., Tsao, Doris Y.
core   +1 more source

An Open Resource for Non-human Primate Imaging [PDF]

open access: yesNeuron, 2017
ABSTRACTNon-human primate neuroimaging is a rapidly growing area of research that promises to transform and scale translational and cross-species comparative neuroscience.Unfortunately, the technological and methodological advances of the past two decades have outpaced the accrual of data, which is particularly challenging given the relatively few ...
Caspar M. Schwiedrzik   +81 more
openaire   +21 more sources

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

Peptide OPTX-1 From Ornithodoros papillipes Tick Inhibits the pS273R Protease of African Swine Fever Virus

open access: yesFrontiers in Microbiology, 2021
African swine fever virus (ASFV) is a large double-stranded DNA virus and causes high mortality in swine. ASFV can be transmitted by biological vectors, including soft ticks in genus Ornithodoros but not hard ticks.
Jingjing Wang   +17 more
doaj   +1 more source

ChimpACT: A Longitudinal Dataset for Understanding Chimpanzee Behaviors [PDF]

open access: yesarXiv, 2023
Understanding the behavior of non-human primates is crucial for improving animal welfare, modeling social behavior, and gaining insights into distinctively human and phylogenetically shared behaviors. However, the lack of datasets on non-human primate behavior hinders in-depth exploration of primate social interactions, posing challenges to research on
arxiv  

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

open access: yesAdvanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin   +15 more
wiley   +1 more source

The Quest for an Integrated Set of Neural Mechanisms Underlying Object Recognition in Primates [PDF]

open access: yesarXiv, 2023
Visual object recognition -- the behavioral ability to rapidly and accurately categorize many visually encountered objects -- is core to primate cognition. This behavioral capability is algorithmically impressive because of the myriad identity-preserving viewpoints and scenes that dramatically change the visual image produced by the same object.
arxiv  

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

open access: yesAdvanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll   +16 more
wiley   +1 more source

Beyond aerodigestion: exaptation of feeding-related mouth movements for social communication in human and non-human primates [PDF]

open access: yes, 2017
Three arguments are advanced from human and non-human primate infancy research for the exaptation of ingestive mouth movements (tongue-protrusion and lip-smacking) for the purposes of social communication: Their relation to affiliative behaviours; their ...
Bozicevic, Laura   +5 more
core   +2 more sources

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