Results 121 to 130 of about 13,859,723 (285)

[Non-IgE-mediated food allergy].

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
Food allergy is an immune response to proteins in food. It usually affects 8% of children and 2% of adults in Western countries. Non-IgE-mediated food allergy mainly affects the gastrointestinal tract. Gastrointestinal food allergies are classified, by their underlying pathogenesis, as: IgE-mediated, non-IgE-mediated, or mixed. The symptoms of patients
María Isabel, Rojo Gutiérrez, Diego, Ballesteros González, Ana Karen, Ortiz Durán   +2 more
openaire   +1 more source

Non-IgE-mediated gastrointestinal food allergy. Updated literature review by the CMICA Food Allergy Committee

Revista Alergia México
Background: Non-IgE-mediated gastrointestinal food allergy includes adverse reactions to food mediated by the innate immune system and cellular immunity. It is characterized by subacute or chronic gastrointestinal symptoms after ingestion of a relevant food allergen, making diagnosis difficult.
Ileana María, Madrigal-Beas, Jonathan Higgins, Payan-Díaz, Alejandra, Medina-Hernández, María Gracia Belinda, Guerrero-Núñez, María de Los Angeles, Juan-Pineda, Daniela, Rivero-Yeverino, Blanca María, Morfin-Maciel   +6 more
openaire   +2 more sources

Natural History of Alternaria Sensitisation and Association With Asthma and Rhinitis From Childhood to Adulthood

Allergy, EarlyView.
We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily, Hongmei Zhang, Graham Roberts, Pandurangan Vijayanand, Magnus Borres, Eva Södergren, Ramesh J. Kurukulaaratchy, S. Hasan Arshad   +7 more
wiley   +1 more source

Development of IgE-mediated food allergies in children with history of food protein-induced allergic proctocolitis: a series of five cases

Frontiers in Allergy
Food protein-induced allergic proctocolitis (FPIAP) is a non-IgE-mediated allergic condition that presents with hematochezia in otherwise healthy infants. It is most commonly induced by cow's milk protein via breast milk or formula.
Kim L. Tran, Elizabeth L. Wisner, Elizabeth L. Wisner, George M. Jeha, Luke A. Wall, Luke A. Wall   +5 more
doaj   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Skin and gut microbiota composition and immune regulatory response differentiate IgE and non-IgE cow’s milk allergy patients with atopic dermatitis

iScience
Summary: Precise identification of food allergy and atopic dermatitis (AD) endotypes in infants is needed to target treatments effectively. Therefore, we investigated markers associated with changes in the microbiota and immune responses within the gut ...
Tomas Thon, Eliska Kopelentova, Dagmar Srutkova, Stepan Coufal, Jakub Kreisinger, Filip Rob, Zuzana Reiss, Miloslav Kverka, Stepanka Capkova, Jana Cadova, Lucie Bulantova, Vojtech Bystry, Anna Sediva, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska, Andrea Polouckova   +15 more
doaj   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

Allergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang   +18 more
wiley   +1 more source

Influence of the gut microbiome on IgE and non-IgE-mediated food allergies [PDF]

, 2018
Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- MAY 26-30, 2018 -- Munich, GERMANYWOS: 000441690400204Background: The prevalence of food allergy (FA) in children has been increasing in last decade.
Aktaş, Özge, Sackesen, Cansın, Uslu Kızılkan, Nuray, Kaya, A., Perkins, D. L., Finn, Patricia, Öztürk, Ayşe Bilge, Arık Yılmaz, Ebru, Metwally, AboBakr, Yazıcı, Duygu, Turturice, Benjamin, Nacaroğlu, Tekin   +11 more
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