Results 131 to 140 of about 13,859,723 (285)

Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy

Allergy, EarlyView.
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios, Alejandro Gonzalo‐Fernández, Natalia Freundt‐Serpa, Guadalupe Marco‐Martín, Beatriz Fernández‐Parra, María Isabel Alvarado‐Izquierdo, Rocío Casas‐Saucedo, Cristina Stein‐Coronado, Ethel Ibáñez‐Echevarría, Tania Ramos‐García, María Dolores Alonso‐Díaz de Durana, Azahara López‐Raigada, Carlos Blanco‐Guerra, María Pía de Calzada‐Bustingorri, Teresa Carrillo‐Díaz, Hilda Rianec Hernández‐Suárez, Miguel Ángel Díaz‐Palacios, Sonsoles Infante‐Herrero, Ana María Nieto‐Nieto, Sonia Vázquez‐Cortés, Eloína González‐Mancebo, María M. Escribese, Pilar Rico‐Nieto, Domingo Barber, Montserrat Fernández‐Rivas   +24 more
wiley   +1 more source

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source

Role of Cysteinyl Leukotrienes in Food Allergy and Anaphylaxis: A Potential Therapeutic Target

Allergy, EarlyView.
Adrienn Weingärtner, Thomas Eiwegger
wiley   +1 more source

A pediatrician's guide to gastrointestinal allergies

Лечащий Врач
Background. Cow's milk allergy is one of the most common food allergies in children. Gastrointestinal forms of food allergy require special attention from the pediatrician, but they still remain poorly recognized.
O. Kh. Konobeitsev
doaj   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source

Multicenter food protein–induced enterocolitis syndrome (FPIES) data collection: Leveraging a REDCap FPIES registry for improved clinical outcomes

Journal of Allergy and Clinical Immunology: Global
Background: Food protein–induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy typically presenting in infancy but has also been recognized in adults.
Ankona Banerjee, MSc, J. Andrew Bird, MD, Amy M. Scurlock, MD, Pooja Varshney, MD, Elizabeth Brunner, MD, Ankur Bhagwath, BSc, Benjamin Daines, MD, Malika Gupta, MD, Tevon Hood, DO, Maria Lee, MD, Michelle Lee, BScA, Emily Seminara, BA, Rachel Smith, RN, Gail Tan, MD, Marion Jose Valladares, MD, Hiral Waghela, MD, Duc T. Nguyen, MD, PhD, Sara Anvari, MD, MSc   +17 more
doaj   +1 more source

Global Variation in Timing of Allergenic Food Introduction for Food Allergy Prevention: An International Survey of Healthcare Professionals

Allergy, EarlyView.
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung, Elizabeth Huiwen Tham, Kiwako Yamamoto‐Hanada, Derek K. Chu, Matthew Norris, Daria Levina, Daniel Munblit, Lamia Dahdah, Luciana Kase Tanno, Carmen Riggioni, Elsy M. Navarrete‐Rodriguez, Michael E. Levin, Thulja Trikamjee, William Guo, Chun Tong Lei, Chun Pong Lau, Supinda Bunyavanich, Nikolaos G. Papadopoulos, Adnan Custovic, Christina West, Gary Wing‐kin Wong   +20 more
wiley   +1 more source

A nationwide survey of non-IgE-mediated gastrointestinal food allergies in neonates and infants

Allergology International
Non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFAs) seem to be increasing rapidly worldwide. However, nationwide studies have been limited to food-protein-induced enterocolitis (FPIES) and food-protein-induced allergic proctocolitis (FPIAP), with little attention to other non-IgE-GIFA subgroups.
Hiroko Suzuki, Naho Morisaki, Saori Nagashima, Tamotsu Matsunaga, Shoko Matsushita, Akira Iino, Yuichiro Tanaka, Hisashi Nishimori, Shun Munakata, Manabu Kemmochi, Yoshitaka Murakami, Miori Sato, Kenji Toyokuni, Kiwako Yamamoto-Hanada, Hideaki Morita, Tatsuki Fukuie, Yoshiyuki Yamada, Yoshikazu Ohtsuka, Katsuhiro Arai, Yukihiro Ohya, Hirohisa Saito, Kenji Matsumoto, Ichiro Nomura   +22 more
openaire   +3 more sources