An athletic approach to studying perception-action integration: Does sport-specific training, and the impact of injury, influence how individuals visually guide navigation? [PDF]
, 2015 The objective of this thesis was to investigate perception-action integration capabilities of individuals during a choice navigation task. This task assessed navigation strategies in open space while individuals avoided colliding with two vertical ...
Baker, Carmen +2 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Emergence of nonmotor symptoms as the focus of research and treatment of Parkinson's disease: Introduction to the special section on nonmotor dysfunctions in Parkinson's disease [PDF]
, 2013 Parkinson's disease (PD) is traditionally characterized by the cardinal motor symptoms of tremor, rigidity, slowness of movement, and impairments of posture, gait, and balance.
Cronin-Golomb, Alice
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Videonystagmography features and clinical symptoms correlate with Parkinson's clinical subtypes
Frontiers in NeurologyObjectiveAnalyzing the differences in video-nystagmography (VNG) parameters among Parkinson's disease (PD) patients with distinct motor subtypes and evaluate the correlation between VNG parameters and the severity of non-motor symptoms (NMS) in Tremer ...
Guangli Zheng +6 more
doaj +1 more source
New advanced wireless technologies for objective monitoring of motor symptoms in parkinson's disease [PDF]
, 2017 Edition of a Research topic of Frontiers in Neurology with 12 reviewed and accepted original papersPeer ReviewedPostprint (published ...
Cabestany Moncusí, Joan +2 more
core +2 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Advances in autonomic dysfunction research in Parkinson’s disease
Frontiers in Aging NeuroscienceParkinson’s disease (PD) is a prevalent neurodegenerative disorder, best known for its motor symptoms such as resting tremor, muscle rigidity, and bradykinesia.
Hongjia Xu +9 more
doaj +1 more source
Parkinsoǹs disease and emerging of imaging tools for prognosis and diagnosis applications [PDF]
, 2016 Parkinson's disease (PD) is a chronicdegenerative neurological disease, characterized by a range of motor (bradykinesia, rigidity, and tremor) and non-motor (fatigue and depression) symptoms in PD, each of which will affect a particular patient to ...
Fatehi, Daryoush. +2 more
core
Psychiatric profile of motor subtypes of de novo drug-naïve Parkinson's disease patients [PDF]
, 2018 Background: Parkinson's disease (PD) is a heterogeneous neurodegenerative disorder. It is well established that different motor subtypes of PD evolve with different clinical courses and prognoses.
Assogna, F +9 more
core +2 more sources