Results 111 to 120 of about 30,589,948 (306)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Organizational change, psychosocial work environment, and non-disability early retirement:a prospective study among senior public employees [PDF]
, 2017 Objective: This study examines the impact of organizational change and psychosocial work environment on non-disability early retirement among senior public service employees.Methods: In January and February 2011, Danish senior public service employees ...
Nina Breinegaard +5 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Work extraction from quantum coherence in non-equilibrium environment
Scientific ReportsErgotropy, which represents the maximum amount of work that can be extracted from a quantum system, has become a focal point of interest in the fields of quantum thermodynamics and information processing.
Maryam Hadipour, Soroush Haseli
doaj +1 more source
, 2020 The purpose of this study was to analyze the effect of the physical work environment and non-physical work environment on employee performance through job satisfaction at PT. MNC Sky Vision Tbk Medan.
Fahriani Astuti Sitepu +2 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Indonesian Management and Accounting ResearchThe purpose of this research is to investigate the factors of intention to quit, which is the final decision made if the employee is dissatisfied with the job and its environment. This includes the physical work environment, non-physical work environment, and role conflict experienced by employees.
Fadiyah Indah Pramesti, Ahyar Yuniawan
openaire +1 more source
, 2015 OBJECTIVES: The present study aimed to investigate whether different dimensions of psychosocial stress, as measured by the job demand-control model (JDC), were associated with increased risks of ischemic stroke and coronary heart disease (CHD).METHODS: A
Söderberg, Mia, +9 more
core +1 more source
, 2023 The purpose of this research is to examine and analyze the influence of work load, non-physical work environment and Employee Engagement on the job satisfaction at the PT XYZ. This study used quantitative method.
Sarah, Siti, Primaharanti, Reskha
core +1 more source