Results 61 to 70 of about 1,391,444 (333)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

A Novel Anticancer Peptide Derived from Bryopsis plumosa Regulates Proliferation and Invasion in Non-Small Cell Lung Cancer Cells [PDF]

open access: gold, 2023
Heabin Kim   +10 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Pathogenesis and clinical features of congenital stationary night blindness in case of c.283delC NYX gene mutation

open access: yesРоссийский офтальмологический журнал, 2019
The complete form of X-linked congenital stationary night blindness (CSNB) is a rare genetic disease caused by a mutation in the NYX gene. CSNB is associated with the mutations taking place in 17 genes, whilst its CSNB1A form is caused by the mutations ...
M. E. Ivanova   +6 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

EU’S POLICY OF DISARMAMENT AS PART OF ITS NORMATIVE POWER [PDF]

open access: yesCES Working Papers, 2015
This article argues that EU’s policy of Disarmament, Non-Proliferation, and Arms Export Control can be conceptualised into the framework of the normative power.
Roxana HINCU
doaj  

US nuclear non-proliferation policy and Ukraine

open access: yesАмериканська історія і політика, 2017
The article deals with some aspects of US policy in the sphere of non-proliferation of nuclear weapons and Washington’s influence on the processes denuclearization Ukraine in 1992-1996.
Oleksandr Potiekhin
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The Effect of Non Freeze-dried Hydrogel-CHA on Fibroblast Proliferation

open access: yesJournal of Dentistry Indonesia, 2015
Bone damage can be caused by variety of surgical procedures. Bone reconstruction has been developed lately is tissue engineering techniques. One of materials that proved to be effective as a scaffold in tissue engineering is a hydrogel.
Ivan Arie Wahyudi   +1 more
doaj   +1 more source

Joining the Non-Proliferation Treaty

open access: yes, 2018
List of contributors Introduction (Yoko Iwama) Part I 1. Nuclear Proliferation and Conceptions of National Interest: The U.S. Case, 1960-1967 (William Burr) 2. After the Hegemony of the "Atoms for Peace" Programmeme: Multilateral Non-proliferation Policy under the Nixon and Ford Administrations (Shinsuke TOMOTSUGU) Part II 3.
openaire   +3 more sources

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