Results 71 to 80 of about 12,220,401 (374)

Sherlock Holmes Meets Rube Goldberg: Fixing the Entry-into-Force Provisions of the Comprehensive Nuclear Test Ban Treaty [PDF]

open access: yes, 2016
The Comprehensive Nuclear Test Ban Treaty (CTBT) is widely heralded as the most important international legal instrument for arresting the nuclear arms race and impeding further nuclear proliferation.
Koplow, David A.
core   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The Effect of Non Freeze-dried Hydrogel-CHA on Fibroblast Proliferation

open access: yesJournal of Dentistry Indonesia, 2015
Bone damage can be caused by variety of surgical procedures. Bone reconstruction has been developed lately is tissue engineering techniques. One of materials that proved to be effective as a scaffold in tissue engineering is a hydrogel.
Ivan Arie Wahyudi   +1 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Investigation of nuclear material using a compact modified uniformly redundant array gamma camera

open access: yesNuclear Engineering and Technology, 2018
We developed a compact gamma camera based on a modified uniformly redundant array coded aperture to investigate the position of a UO2 pellet emitting characteristic X-rays (98.4 keV) and γ-rays (185.7 keV).
Taewoong Lee, Sung-Woo Kwak, Wonho Lee
doaj   +1 more source

Nuclear disarmament and non proliferation a view to posible changes. [PDF]

open access: yes, 2012
This paper called “Nuclear Disarmament and Non Proliferation: A view to possible changes” is a result of a wide investigation about this relevant topic in the international scope.
Ante Levoyer, Felipe
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

EU Foreign Policy Identity: A Case Study on the EU’s Engagement of the Islamic Republic of Iran. College of Europe EU Diplomacy Paper 06/2019 [PDF]

open access: yes, 2019
The Joint Comprehensive Plan of Action (JCPOA) is often referred to as the biggest foreign policy success of the European Union (EU). It ended twelve years of tough negotiations, stabilising one of the most volatile regions of the world.
McCloskey-Gholikhany, Leah
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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