Results 101 to 110 of about 617,984 (298)
NON-PROPORTIONAL HAZARDS WITH APPLICATION TO KIDNEY TRANSPLANT DATA
Communications, Faculty Of Science, University of Ankara Series A1Mathematics and Statistics, 1999 The Cox proportional hazards (PH) model is the popular methodfor modelling censored survival data.Cox PH model is the proportionality of hazards in which the hazard ratiois linear in the covariates. However this assumption may not hold in somesurvival studies.
openaire +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Bayesian Analysis of Hazard Regression Models under Order Restrictions on Covariate Effects and Ageing [PDF]
, 2007 We propose Bayesian inference in hazard regression models where the baseline hazard is unknown, covariate effects are possibly age-varying (non-proportional), and there is multiplicative frailty with arbitrary distribution.
Bhattacharjee, Arnab +1 more
core +4 more sources
Modelling non-proportional hazard for survival data with different systematic components
Environmental and Ecological Statistics, 2020 We propose a new extended regression model based on the logarithm of the generalized odd log-logistic Weibull distribution with four systematic components for the analysis of survival data. This regression model can be very useful and could give more realistic fits than other special regression models.
Fábio Prataviera +4 more
openaire +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2020 Acute myocardial infarction (AMI) is a leading cause of death and not a few of these patients are combined with acidemia. This study aimed to detect the association of acidemia with short-term mortality of AMI patients.
Tang Zhang, Yao-Zong Guan, Hao Liu PhD
doaj +1 more source
Incorporation of Frailties Into a Non-Proportional Hazard Regression Model and Its Diagnostics for Reliability Modeling of Downhole Safety Valves [PDF]
, 2020 Francisco Louzada +15 more
openalex +1 more source
, 2018 The Cox model, which remains as the first choice in analyzing time-to-event data even for large datasets, relies on the proportional hazards assumption. When the data size exceeds the computer memory, the standard statistics for testing the proportional ...
Schifano, Elizabeth D. +3 more
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Modeling multilevel sleep transitional data via Poisson log-linear multilevel models [PDF]
, 2009 This paper proposes Poisson log-linear multilevel models to investigate population variability in sleep state transition rates. We specifically propose a Bayesian Poisson regression model that is more flexible, scalable to larger studies, and easily ...
Brian S. Caffo +4 more
core +2 more sources