Results 31 to 40 of about 12,711,695 (243)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The non-reciprocal Dicke model [PDF]

open access: yes, 2023
We investigate the physics of an open two-component Dicke model, where the light field mediates non-reciprocal interactions between two spin species.
Nunnenkamp, Andreas   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Wetting and pattern formation in non-reciprocal ternary phase separation

open access: yesNew Journal of Physics
Non-reciprocal interactions are among the simplest mechanisms that drive a physical system out of thermal equilibrium, leading to novel phenomena such as oscillatory pattern formation.
Xiao Ma, Michael E Cates
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Multibody and Non-Reciprocal Interactions in Acoustically Levitated Granular Systems [PDF]

open access: yes
Particles interacting via a non-equilibrium fluid often violate the principle of reciprocity after the fluid is coarse-grained away. The lack of reciprocity means that neither energy nor momentum are conserved and can be continuously extracted from the ...
Wu, Bin
core   +1 more source

Non-reciprocal multifarious self-organization

open access: yes, 2022
A hallmark of living systems is the ability to employ a common set of building blocks that can self-organize into a multitude of different structures.
Osat, S.   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Collective motion of active particles exhibiting non-reciprocal orientational interactions

open access: yes, 2023
We present a Brownian dynamics study of a 2D bath of active particles interacting among each other through usual steric interactions and, additionally, via non-reciprocal avoidant orientational interactions.
Knežević, Miloš   +2 more
core   +1 more source

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