Results 51 to 60 of about 12,711,695 (243)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Authority and Deliberative Moments: Assessing Equality and Inequality in Deeply Divided Groups

open access: yesJournal of Deliberative Democracy, 2017
The notion of equality is central to public deliberation, but few researches have examined how participants construct interactions in face-to-face group discussion involving unequal conditions of authority.
Danila Cal   +5 more
doaj   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Neural correlate of human reciprocity in social interactions

open access: yesFrontiers in Neuroscience, 2013
Reciprocity plays a key role maintaining cooperation in society. However, little is known about the neural process that underpins human reciprocity during social interactions.
Shiro eSakaiya   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Online and in-store shopping interactions for non-essential experience goods

open access: yesComputational Urban Science, 2023
The online and in-store shopping landscape underwent transformative shifts due to the Covid-19 pandemic, potentially leading to novel hybrid shopping behaviors following the availability of Covid-19 vaccines.
Ibukun Titiloye   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Perfect chirality constructed by position-dependent backscattering in a whispering gallery mode microresonator

open access: yesNew Journal of Physics
Unidirectional propagation of photons originated from perfect chirality meets the critical requirement for building a high-performance quantum network.
Xin-Yue Ma   +5 more
doaj   +1 more source

The Double-Aspect of Life

open access: yesBiology, 2018
Life is based on two aspects: matter and a non-material, electrical component. In a dynamic system of reciprocal causality, matter and the so-called bioelectricity interact with one another, forming a functional unity.
Daniel Fels
doaj   +1 more source

Indirect genetic effects and housing conditions in relation to aggressive behaviour in pigs. [PDF]

open access: yesPLoS ONE, 2013
Indirect Genetic Effects (IGEs), also known as associative effects, are the heritable effects that an individual has on the phenotype of its social partners.
Irene Camerlink   +3 more
doaj   +1 more source

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