Results 41 to 50 of about 12,711,695 (243)

Within-host dynamics of multi-species infections: facilitation, competition and virulence. [PDF]

open access: yesPLoS ONE, 2012
Host individuals are often infected with more than one parasite species (parasites defined broadly, to include viruses and bacteria). Yet, research in infection biology is dominated by studies on single-parasite infections.
Sandeepa M Eswarappa   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Impact of Reciprocity in Information Spreading Using Epidemic Model Variants

open access: yesInformation, 2018
The use of online social networks has become a standard medium of social interactions and information spreading. Due to the significant amount of data available online, social network analysis has become apropos to the researchers of diverse domains to ...
Rishabh Narang   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Non-covalent Interactions in Coordination and Organometallic Chemistry

open access: yes, 2022
Non-covalent interactions in coordination and organometallic compounds (hydrogen, halogen, chalcogen, pnictogen, tetrel, and semi-coordination bonds; agosic and anagosic interactions; stacking, anion-/cation-π interactions; metallophilic interactions ...

core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Symmetry breaking-induced N-body electrodynamic forces in optical matter systems

open access: yesNature Communications
Breaking symmetry can give rise to non-reciprocal forces–unequal and opposite forces–typically observed in active matter systems involving asymmetric 2-body interactions.
John Parker   +6 more
doaj   +1 more source

The XY model with vision cone: non-reciprocal vs. reciprocal interactions [PDF]

open access: yes
We study the behavior of the classical XY model on a two-dimensional square lattice, with interactions occurring within a vision cone of each spin. Via Monte Carlo simulations, we explore one non-reciprocal and two reciprocal implementations of these ...

core   +3 more sources

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