Results 201 to 210 of about 10,520,469 (283)

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source

Comparative evaluation of pure non-<i>Saccharomyces</i> yeasts fermentation and Lactiplantibacillus plantarum co-fermentation in fig pulp: Achieving remarkable sugar reduction and flavor enhancement. [PDF]

Food Chem X
Chen K, Gong Z, Wu C, Rong W, Zhang T, Li Q, Lei H.   +6 more
europepmc   +1 more source

Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance

The FEBS Journal, EarlyView.
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley   +1 more source

Rescue of pATOM36‐depleted T. brucei by human MTCH1/2 reveals common features of protein insertases

The FEBS Journal, EarlyView.
Human MTCH1 and MTCH2 (with an N‐terminal extension) functionally complement the loss of pATOM36 in T. brucei, indicating that these evolutionarily distant proteins recognize a common set of substrates and share fundamental principles of mitochondrial outer membrane protein insertion. Structural analyses reveal a common hydrophilic cavity, supporting a
Stephan Berger, Markus Daniel Gerber, Torsten Ochsenreiter, Christoph von Ballmoos, André Schneider   +4 more
wiley   +1 more source

Climate Change Adaptation in Winemaking: Combined Use of Non-<i>Saccharomyces</i> Yeasts to Improve the Quality of Pedro Ximénez Wines. [PDF]

Microorganisms
Sánchez-Suárez F, Martínez-García R, Peinado RA.   +2 more
europepmc   +1 more source

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

The FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

UbiB proteins mediate an ATP‐dependent decarboxylation step in bacterial ubiquinone biosynthesis

The FEBS Journal, EarlyView.
UbiB proteins are atypical protein kinase‐like enzymes essential for ubiquinone biosynthesis. Here, we demonstrate that bacterial UbiB proteins catalyze the O2‐dependent decarboxylation of ubiquinone precursors, a process linked to their ATPase activity.
Katayoun Kazemzadeh, Bruno Faivre, Sophie‐Carole Chobert, Martial Rey, Sophie S. Abby, Julie Michaud, Tuan‐Anh Dinh, Alexandre Chilin, Olivier Lerouxel, Marc Fontecave, Fabien Pierrel, Murielle Lombard, Ludovic Pelosi   +12 more
wiley   +1 more source

Modulation of Aromatic Amino Acid Metabolism by Indigenous Non-Saccharomyces Yeasts in Croatian Maraština Wines. [PDF]

Foods
Boban A, Vrhovsek U, Anesi A, Milanović V, Gajdoš Kljusurić J, Jurun Z, Budić-Leto I.   +6 more
europepmc   +1 more source

The transport of protein aggregates to the vacuole suggests a role for lipid droplets in waste disposal in Saccharomyces cerevisiae

The FEBS Journal, EarlyView.
Lipid droplets (LD) act as cellular ‘garbage trucks’ that transport cytosolic protein aggregates to the vacuole for degradation in yeast. Protein aggregates are docked to lipid droplets in a triacylglycerol‐dependent manner, transported through the cytoplasm, and transferred to the insoluble protein deposit (IPOD) at the vacuole.
Christoph Reiter, Patrick Ebner, Elli Leona Kronsteiner, Sophia Moustakakis, Markus Wiederstein, Astrid Obermayer, Ronald Thomas Huber, Christian Schloegelhofer, Florian Wieser, Jon Cedrick Richter, Isabelle Guirsch, Patrick Rockenfeller, Jana Vojtová, Tomáš Groušl, Thomas Klaus Felder, Mark Rinnerthaler   +15 more
wiley   +1 more source

The Antioxidant Capacity and Flavor Diversity of Strawberry Wine Are Improved Through Fermentation with the Indigenous Non-<i>Saccharomyces</i> Yeasts <i>Hanseniaspora uvarum</i> and <i>Kurtzmaniella quercitrusa</i>. [PDF]

Foods
Wang R, Yang B, Jia S, Dai Y, Lin X, Ji C, Chen Y.   +6 more
europepmc   +1 more source