Results 31 to 40 of about 346,212 (321)

One vaccine to counter many diseases? Modeling the economics of oral polio vaccine against child mortality and COVID-19

Frontiers in Public Health, 2022
IntroductionRecent reviews summarize evidence that some vaccines have heterologous or non-specific effects (NSE), potentially offering protection against multiple pathogens.
Angela Y. Chang, Angela Y. Chang, Peter Aaby, Peter Aaby, Michael S. Avidan, Christine S. Benn, Christine S. Benn, Christine S. Benn, Stefano M. Bertozzi, Stefano M. Bertozzi, Stefano M. Bertozzi, Lawrence Blatt, Lawrence Blatt, Konstantin Chumakov, Konstantin Chumakov, Shabaana A. Khader, Shyam Kottilil, Shyam Kottilil, Madhav Nekkar, Mihai G. Netea, Mihai G. Netea, Mihai G. Netea, Annie Sparrow, Dean T. Jamison   +23 more
doaj   +1 more source

Effect of national immunisation campaigns with oral polio vaccine on all-cause mortality in children in rural northern Ghana: 20 years of demographic surveillance cohort dataResearch in context

EClinicalMedicine, 2023
Summary: Background: Studies from Guinea-Bissau and Bangladesh have shown that campaigns with oral polio vaccine (C-OPV) may be associated with 25–31% lower child mortality. Between 1996 and 2015, Ghana had 50 national C-OPVs and numerous campaigns with
Paul Welaga, Martin Kavao Mutua, Syed Manzoor Ahmed Hanifi, Patrick Ansah, Peter Aaby, Sebastian Nielsen   +5 more
doaj   +1 more source

Non-specific effects of veterinary vaccines: a systematic review

Vaccine, 2022
The benefits of vaccines have been centred on their specific effects on subsequent infections by target pathogens. Recent studies, however, have opened up new insights into additional effects of vaccines known as non-specific effects (NSEs) or heterologous effects of vaccines.
Arega, Sintayehu, Knobel, Darryn Leslie, Toka, Felix N., Conan, Anne   +3 more
openaire   +3 more sources

Parental Bacillus Calmette-Guérin vaccine scars decrease infant mortality in the first six weeks of life: A retrospective cohort study

EClinicalMedicine, 2021
Background: Live attenuated vaccines have been observed to have particularly beneficial effects for child survival when given in the presence of maternally transferred immunity (priming).
MLT Berendsen, F. Schaltz-Buchholzer, P. Bles, S. Biering-Sørensen, KJ. Jensen, I. Monteiro, I. Silva, P. Aaby, CS. Benn   +8 more
doaj   +1 more source

Non-specific effects of BCG vaccine on viral infections [PDF]

Clinical Microbiology and Infection, 2019
Some strains of Bacillus Calmette-Guérin (BCG) vaccine not only confer protection against disseminated forms of tuberculosis, but also reduce all-cause mortality by the induction of protection against infections with non-related pathogens.We review evidence for non-specific protection induced by BCG vaccination against viral infections, discuss ...
Moorlag, S.J.C.F.M., Arts, R.J.W., van Crevel, R., van Crevel, R., Netea, M.G., Netea, M.G.   +5 more
openaire   +3 more sources

LIMITATIONS OF THE CONTEMPORARY VACCINES: HOW TO OVERCOME ? [PDF]

Exploratory Animal and Medical Research, 2023
Vaccines are used generally to prevent a few infectious diseases by stimulating the weapons of acquired immunity of the body against specific antigens.
Shibabrata Pattanayak
doaj   +1 more source

Is early measles vaccination associated with stronger survival benefits than later measles vaccination?

BMC Public Health, 2018
Background Measles vaccine (MV) may protect against non-measles mortality. We tested whether survival depended on age of measles vaccination. Methods Bandim Health Project follows children under 5 years of age through a Health and Demographic ...
Jesper Sloth Hansen, Sanne Marie Thysen, Amabelia Rodrigues, Cesario Martins, Ane Bærent Fisker   +4 more
doaj   +1 more source

Non-specific “non-effects” of vaccination [PDF]

BMJ, 2004
This issue carries a paper from Burkina Faso on the non-specific effects of vaccination on survival in children (p1309).1 The study analyses mortality in a cohort of children as a function of their vaccination status. The authors conclude that vaccination with diphtheria, tetanus, and pertussis (DTP) vaccine as well as BCG is associated with better ...
openaire   +2 more sources

Measles Vaccination Supports Millennium Development Goal 4: Increasing Coverage and Increasing Child Survival in Northern Ghana, 1996–2012

Frontiers in Public Health, 2018
BackgroundMeasles vaccine (MV) administered as the last vaccine after the third dose of diphtheria-tetanus-pertussis (DTP) may be associated with better child survival unrelated to prevention of measles infection.
Paul Welaga, Paul Welaga, Abraham Hodgson, Cornelius Debpuur, Peter Aaby, Peter Aaby, Fred Binka, Daniel Azongo, Abraham Oduro   +8 more
doaj   +1 more source

Heterologous vaccine interventions: boosting immunity against future pandemics

Molecular Medicine, 2021
While vaccines traditionally have been designed and used for protection against infection or disease caused by one specific pathogen, there are known off-target effects from vaccines that can impact infection from unrelated pathogens.
Daniela Marín-Hernández, Douglas F. Nixon, Nathaniel Hupert   +2 more
doaj   +1 more source