Results 51 to 60 of about 385 (111)

Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections

Frontiers in Immunology, 2019
The central paradigm of vaccination is to generate resistance to infection by a specific pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two fundamental characteristics of the adaptive immune system, specificity and ...
Babita Agrawal
doaj   +1 more source

Complete and on-time routine childhood immunisation: determinants and association with severe morbidity in urban informal settlements, Nairobi, Kenya

Annals of Human Biology, 2020
Background: Completion of the full series of childhood vaccines on-time is crucial to ensuring greater protection against vaccine-preventable diseases. Aim: To examine determinants of complete and on-time vaccination and evaluate the relationship between
Martin K. Mutua, Shukri F. Mohamed, Elizabeth W. Kimani-Murage, Lucy Kiarie, Cara Bess Janusz, Peter Aaby, Ane B. Fisker, Elizabeth Echoka, Henrik Ravn   +8 more
doaj   +1 more source

The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs

Frontiers in Immunology, 2019
Background: Vaccines may have non-specific effects, affecting resistance to heterologous pathogens. Veterinary vaccines have seldom been investigated for their non-specific effects.
Kristoffer Jarlov Jensen, Kristoffer Jarlov Jensen, Mette Sif Hansen, Peter Mikael Helweg Heegaard, Christine Stabell Benn, Christine Stabell Benn, Gregers Jungersen   +6 more
doaj   +1 more source

Cohort Profile: Childhood morbidity and potential non-specific effects of the childhood vaccination programmes in the Nordic countries (NONSEnse): register-based cohort of children born 1990–2017/2018

BMJ Open, 2023
Purpose The aim of the NONSEnse project is to investigate the non-specific effects of vaccines and immunisation programmes on the overall health of children by using information from the extensive nationwide registers on health and sociodemographic ...
Christine Stabell Benn, Signe Sørup, Berit Feiring, Ida Laake, Lill Trogstad, Arto A Palmu, Lise Gehrt, Hélène Englund, Heta Nieminen, Mika Lahdenkari   +9 more
doaj   +1 more source

Non-specific Effect of Vaccines: Immediate Protection against Respiratory Syncytial Virus Infection by a Live Attenuated Influenza Vaccine

Frontiers in Microbiology, 2018
The non-specific effects (NSEs) of vaccines have been discussed for their potential long-term beneficial effects beyond direct protection against a specific pathogen.
Young J. Lee, Jeong Y. Lee, Yo H. Jang, Sang-Uk Seo, Jun Chang, Jun Chang, Baik L. Seong, Baik L. Seong   +7 more
doaj   +1 more source

Do measles vaccines have non-specific effects on mortality?

Bulletin of the World Health Organization, 2005
Editor--Cooper et al. (1) reviewed the non-specific effects on mortality of childhood vaccines. Although there are numerous studies detailing mortality following measles vaccination (MV) (2), only two studies cited in their article (3, 4) satisfied the authors' methodological criteria.
Henrik Jeldtoft Jensen, Peter Aaby
openaire   +4 more sources

Hypothesis: Vitamin A supplementation and childhood mortality: amplification of the non-specific effects of vaccines? [PDF]

International Journal of Epidemiology, 2003
Most areas of health research will have accepted data and a dominating interpretation. If the interpretation is not correct, contradictions will accumulate, and it will eventually become clear that the current interpretation is untenable. In this situation, the best hypothesis is the one that accounts for all of the known data as well as the apparent ...
Christine Stabell Benn, Henrik Friis, Carlitos Balé, Peter Aaby, Halvor Sommerfelt   +4 more
openaire   +3 more sources

Evidence of Increase in Mortality After the Introduction of Diphtheria–Tetanus–Pertussis Vaccine to Children Aged 6–35 Months in Guinea-Bissau: A Time for Reflection?

Frontiers in Public Health, 2018
BackgroundWhole-cell diphtheria–tetanus–pertussis (DTP) and oral polio vaccine (OPV) were introduced to children in Guinea-Bissau in 1981. We previously reported that DTP in the target age group from 3 to 5 months of age was associated with higher ...
Peter Aaby, Peter Aaby, Søren Wengel Mogensen, Amabelia Rodrigues, Christine S. Benn, Christine S. Benn   +5 more
doaj   +1 more source

Non-specific effects of vaccines in developing countries [PDF]

BMJ, 2000
Papers p 1435 Immunisation has led to spectacular reductions in mortality in both developed and developing countries.1 However, we know too little about the overall effect of vaccines. We have taken vaccines and schedules that are effective in developed countries with low levels of childhood mortality and used them in populations with high death ...
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Non-specific effects of vaccination on child survival: prospective cohort study in Burkina Faso [PDF]

BMJ, 2004
To study the effect of vaccination on mortality before 2 years of age in a developing country.Prospective cohort study.Rural communities in Burkina Faso.9085 children born in the study area between 1985 and 1993.Child death rate.Mortality before 2 years of age was lower in children who had been vaccinated: those vaccinated with BCG only had ...
/Vaugelade, Jacques, Pinchinat, S., Guiella, G., /Elguero, Eric, /Simondon, François   +4 more
openaire   +3 more sources