Results 51 to 60 of about 346,212 (321)

Protective immunity against Trypanosoma cruzi [PDF]

, 2009
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel, Padilla, Ángel Marcelo, Parodi Ramoneda, Cecilia María   +2 more
core   +1 more source

Evaluation of non-specific effects of human rotavirus vaccination in medical risk infants

Vaccine, 2021
The WHO recommends research into non-specific effects of vaccination. For rotavirus vaccines, these have not yet been well established. We studied non-specific effects up to 18 months of age using data from a quasi-experimental before-after study comparing cohorts of rotavirus vaccinated and unvaccinated infants with medical risk conditions.Infants ...
Josephine A P, van Dongen, Elsbeth D M, Rouers, Marc J M, Bonten, Patricia C J, Bruijning-Verhagen   +3 more
openaire   +2 more sources

Deletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodes [PDF]

, 2012
<p>Background: Filarial nematodes are tissue-dwelling parasites that can be killed by Th2-driven immune effectors, but that have evolved to withstand immune attack and establish chronic infections by suppressing host immunity. As a consequence, the
AB Fredriksen, AB Pedersen, AE O'Connell, AE Schwab, B de Andres, B Manoury, BL Makepeace, BW Li, C Klotz, C Martin, C Martin, D Abraham, D Abraham, D Horst, D Knox, David W. Taylor, DH Barouch, DL Redmond, E Maraskovsky, G Ahlen, G Nchinda, GT Joseph, HA Farid, HongLin Luo, J Gardon, J Murray, JE Allen, JE Allen, JJ Donnelly, JP Hewitson, Judith E. Allen, KJ Fairlie-Clarke, KJ Ishii, LM Mir, LM Mir, LvG Jørgensen, MD Taylor, MD Taylor, MY Osei-Atweneboana, N Gomez-Escobar, Nick Gray, O Golden, PJ Hotez, R Ihaka, RM Maizels, RT Rwegoshora, S Babayan, S Frontier, S Mendez, S Ramachandran, S Thirugnanam, SA Babayan, SA Babayan, SB Anand, SB Anand, SB Anand, Simon A. Babayan, SM Sumida, Stephen John Davies, W Harnett, WF Gregory, WF Gregory, Y Dash, Y Wu   +63 more
core   +4 more sources

Implications of the non-specific effect induced by Bacillus Calmette-Guerin (BCG) vaccine on vaccine recommendations

Jornal de Pediatria, 2023
Since the beginning of its use for the prevention of tuberculosis (TB) in 1921, other uses of BCG (Bacillus Calmette-Guérin) have been proposed, particularly in the treatment of malignant solid tumors, multiple sclerosis, and other autoimmune diseases.
Ekaterini Goudouris, Carolina Sanchez Aranda, Dirceu Solé   +2 more
openaire   +3 more sources

A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [PDF]

, 2014
Strategies to optimize responses to seasonal influenza vaccination in older adults include the use of adjuvants, higher antigen doses, and intradermal delivery.
Castellino, Flora, Clement, Frédéric, Del Giudice, Giuseppe, Della Cioppa, Giovanni, Galli, Grazia, Groth, Nicola, Leroux-Roels, Geert, Levin, Yotam, Lindert, Kelly, Nicolay, Uwe   +9 more
core   +1 more source

Trust in scientists on climate change and vaccines [PDF]

, 2015
On climate change and other topics, conservatives have taken positions at odds with a strong scientific consensus. Claims that this indicates a broad conservative distrust of science have been countered by assertions that while conservatives might oppose
Hamilton, Lawrence C., Hartter, Joel N., Saito, Kei   +2 more
core   +3 more sources

Unravelling the nature of non-specific effects of vaccines—A challenge for innate immunologists [PDF]

Seminars in Immunology, 2016
Epidemiological observations have shown that vaccines can influence morbidity and mortality more than can be ascribed to target-disease immunity. A growing number of immunological studies have helped identify possible biological mechanisms to explain these so-called nonspecific effects (NSE) of vaccines, including heterologous T-cell reactivity and ...
Kristoffer Jarlov Jensen, Christine Stabell Benn, Reinout van Crevel   +2 more
openaire   +3 more sources

Potential role of specific antibodies as important vaccine induced protective mechanism against Aeromonas salmonicida in rainbow trout. [PDF]

PLoS ONE, 2012
Furunculosis caused by infection with Aeromonas salmonicida subsp. salmonicida has been a known threat to aquaculture for more than a century. Efficient prophylactic approaches against this disease are essential for continued growth of salmonid ...
Kasper Rømer Villumsen, Inger Dalsgaard, Lars Holten-Andersen, Martin Kristian Raida   +3 more
doaj   +1 more source

Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]

, 2019
Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano, De Zutter, Lieven, Garmyn, An, Haesebrouck, Freddy, Heyndrickx, Marc, Martel, An, Pasmans, Frank, Van Rysselberghe, Nathalie, Vandeputte, Jasmien   +8 more
core   +1 more source

Non‐specific effects of vaccination on child survival? A prospective study in Senegal [PDF]

Tropical Medicine & International Health, 2005
SummaryObjectives  Several studies have shown an association between vaccination and child mortality in developing countries. The present paper examines this issue using data from a Senegalese rural area which has been monitored from 1983 to the present.Methods  We analysed two birth cohorts, comprising 7796 and 3573 persons who had received either BCG
Elguero, Eric, Simondon, Kirsten, Vaugelade, Jacques, Marra, Adama, Simondon, François   +4 more
openaire   +3 more sources