Results 71 to 80 of about 18,387,865 (333)

Prediction of protein-protein interaction types using association rule based classification [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Park et alBackground: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient ...
José A Reyes, Kim, JW, Kim, S, Kim Ji, Sangsoo Kim, Gilbert, D, Park, SH, Reyes José A, Reyes, JA, Kim Sangsoo, Park Sung, Ji Kim, David R Gilbert, Gilbert David R, Sung Park   +14 more
core   +1 more source

Studying protein-protein interactions using peptide arrays [PDF]

, 2010
Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T., Rudiger, S.G.D., Sub Cellular Protein Chemistry, Rotem-Bamberger, S., Katz, C., Friedler, A., Levy-Beladev, L., Cellular Protein Chemistry   +7 more
core   +1 more source

The Rift Valley fever accessory proteins NSm and P78/NSm-GN are distinct determinants of virus propagation in vertebrate and invertebrate hosts

Emerging Microbes and Infections, 2014
Rift Valley fever virus (RVFV) is an enzootic virus circulating in Africa that is transmitted to its vertebrate host by a mosquito vector and causes severe clinical manifestations in humans and ruminants.
Felix Kreher, Carole Tamietti, Céline Gommet, Laurent Guillemot, Myriam Ermonval, Anna-Bella Failloux, Jean-Jacques Panthier, Michèle Bouloy, Marie Flamand   +8 more
doaj   +1 more source

The Scottish Structural Proteomics Facility : targets, methods and outputs [PDF]

, 2010
The Scottish Structural Proteomics Facility was funded to develop a laboratory scale approach to high throughput structure determination. The effort was successful in that over 40 structures were determined.
Garrett, Roger A., Barton, Geoffrey J, Mark Dorward (10196177), Prangishvili, D, Muse Oke (452182), Schwarz-Linek, Ulrich, Xu Peng, Melina Kerou (6987863), Catherine H Botting (16216415), James H Naismith (16216433), Prangishvili, D. A., Prakash Patel (594463), David T F Dryden (16216421), Johannes van Niekerk, C. A., C A Johannes van Niekerk (16216409), Carter, Lester G., Taylor, Garry L, Md Arif Sheikh (16216349), Dorward, M, Michal Zawadzki, McMahon, Stephen A., Sheikh, Md Arif, Kerou, Melina, Challis, GL, Muse Oke, Carter, LG, Weikart, Nadine D., James H. Naismith, Oke, M, Challis, Gregory L, McMahon, Stephen A, Yan, X, Malcolm F. White, Xuan Yan (4844139), Liu, Huanting, Melina Kerou, Weikart, Nadine D, van Niekerk, CA, Peter J. Coote, Botting, Catherine H., Michal Zawadzki (11327080), Taylor, GL, David T. F. Dryden, Nadia Kadi (2425486), Prangishvili, David, Sheikh, Md. Arif, Naismith, JH, Schwarz-Linek, Uli, Yan, Xuan, Ulrich Schwarz-Linek, Kadi, N, Coote, Peter J., White, MF, Stephen A. McMahon, Weikart, ND, Carter, Lester G, Kenneth A Johnson (16216388), White, Malcolm F., Overton, IM, Garrett, Roger A, Schmelz, Stefan, Mark Dorward, Kadi, Nadia, Nadia Kadi, Naismith, James H., Liu, H, Garry L Taylor (16216352), Dryden, DT, McMahon, SA, Xuan Yan, Coote, PJ, Niekerk, C. A. Johannes, Lester G. Carter, Zawadzki, M, Overton, Ian M.; id_orcid, Gregory L. Challis, Geoffrey J Barton (16216424), Gregory L Challis (16216427), Ian M Overton (16216406), White, Malcolm F, Lester G Carter (16208402), Stephen A McMahon (16216391), van Niekerk, C A Johannes, Dryden, David T F, Falconer, Helen, Cozens, Christopher, Patel, Prakash, Geoffrey J. Barton, Md. Arif Sheikh, Peng, X, Botting, Catherine H, Barton, Geoffrey J; id_orcid, Roger A Garrett (16216412), Ulrich Schwarz-Linek (5801099), Johnson, KA, Falconer, H, Dorward, Mark, Barton, Geoffrey J., Xu Peng (365714), Huanting Liu (3691537), Peng, Xu, Sheikh, MA, Oke, Muse, Powers, H, Helen Falconer, Nadine D. Weikart, Dryden, David T. F., Prakash Patel, Powers, Helen, Naismith, James H, Malcolm F White (16216430), Kenneth A. Johnson, Taylor, Garry L., Overton, Ian M., Schmelz, S, Catherine H. Botting, Helen Falconer (16216400), Coote, Peter J, Johnson, Kenneth A, Botting, CH, Stefan Schmelz, Kerou, M, Barton, GJ, David Prangishvili (22095), Johnson, Kenneth A., Zawadzki, Michal, Christopher Cozens, David Prangishvili, Nadine D Weikart (16216394), C. A. Johannes van Niekerk, Overton, Ian M, Christopher Cozens (5232944), Garrett, Roger Antony, Peter J Coote (16216418), Challis, Gregory L., Ian M. Overton, Roger A. Garrett, Garrett, RA, Cozens, C, Garry L. Taylor, Helen Powers (16216403), Stefan Schmelz (16216397), Helen Powers, Huanting Liu, Patel, P   +144 more
core   +1 more source

The Structure, Function, and Mechanisms of Action of Enterovirus Non-structural Protein 2C

Frontiers in Microbiology, 2020
Enteroviruses are a group of RNA viruses belonging to the family Picornaviridae. They include human enterovirus groups A, B, C, and D as well as non-human enteroviruses.
Shao-Hua Wang, Kuan Wang, Ke Zhao, S. Hua, Juan Du   +4 more
semanticscholar   +1 more source

Infectious Bronchitis Virus Nonstructural Protein 4 Alone Induces Membrane Pairing

Viruses, 2018
Positive-strand RNA viruses, such as coronaviruses, induce cellular membrane rearrangements during replication to form replication organelles allowing for efficient viral RNA synthesis.
Nicole Doyle, Benjamin W. Neuman, Jennifer Simpson, Philippa C. Hawes, Judith Mantell, Paul Verkade, Hasan Alrashedi, Helena J. Maier   +7 more
doaj   +1 more source

Targeting SARS-COV-2 non-structural protein 16: a virtual drug repurposing study

Journal of Biomolecular Structure and Dynamics, 2020
Non-Structural Protein 16 (nsp-16), a viral RNA methyltransferase (MTase), is one of the highly viable targets for drug discovery of coronaviruses including SARS-CoV-2.
E. Tazikeh-Lemeski, S. Moradi, R. Raoufi, M. Shahlaei, Mehrali Mahmood Janlou, S. Zolghadri   +5 more
semanticscholar   +1 more source

Cryo-EM reveals a double oligomeric ring scaffold of the CHIKV nsP3 peptide in complex with the NTF2L domain of host G3BP1

mBio
Chikungunya virus (CHIKV) poses a severe threat to global public health. The interaction between CHIKV nsP3 and host G3BP1 is critical for viral replication. However, the exact structural mechanism of the nsP3–G3BP1 interaction is scarce. Here, we report
Yuanzhi Liu, Jie Wang, Yinze Han, Xiaoyan Xia, Rui Zeng, Xinyu Fan, Bo Zhang, Kaituo Wang, Jian Lei   +8 more
doaj   +1 more source

Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2

International Journal of Molecular Sciences, 2020
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causing Coronavirus Disease 19 (COVID-19), emerged at the end of 2019 and quickly spread to cause a global pandemic with severe socio-economic consequences.
A. Rogstam, M. Nyblom, S. Christensen, C. Sele, V. O. Talibov, T. Lindvall, A. A. Rasmussen, I. André, Z. Fisher, W. Knecht, F. Kozielski   +10 more
semanticscholar   +1 more source

Influenza Viral Vectors Expressing Two Kinds of HA Proteins as Bivalent Vaccine Against Highly Pathogenic Avian Influenza Viruses of Clade 2.3.4.4 H5 and H7N9

Frontiers in Microbiology, 2018
The H5 and H7N9 subtypes of highly pathogenic avian influenza viruses (HPAIVs) in China pose a serious challenge to public health and the poultry industry.
Jinping Li, Guangyu Hou, Yan Wang, Suchun Wang, Cheng Peng, Xiaohui Yu, Wenming Jiang   +6 more
doaj   +1 more source