Results 61 to 70 of about 18,387,865 (333)
Vaccines, 2022 Foot-and-mouth disease (FMD) is an economically important and highly infectious viral disease, predominantly controlled by vaccination. The removal of non-structural proteins (NSPs) is very important in the process of FMD vaccine production, because ...
Sun Young Park +12 more
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Effects of NMR spectral resolution on protein structure calculation [PDF]
, 2013 Adequate digital resolution and signal sensitivity are two critical factors for protein structure determinations by solution NMR spectroscopy. The prime objective for obtaining high digital resolution is to resolve peak overlap, especially in NOESY ...
Victor Jaravine +15 more
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SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment
Frontiers in Immunology, 2020 The emergence and rapid spread of SARS-CoV-2 in December 2019 has brought the world to a standstill. While less pathogenic than the 2002–2003 SARS-CoV, this novel betacoronavirus presents a global threat due to its high transmission rate, ability to ...
Khalil Khalaf +7 more
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Viruses, 2023 The porcine reproductive and respiratory syndrome virus (PRRSV) causes economic losses in the swine industry worldwide. However, current vaccines cannot provide effective protection against PRRSV, and PRRSV-specific treatments for infected herds are ...
Zhenbang Zhu +4 more
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Protein-Ligand Interactions: Docking, Design and Conformation Change [PDF]
, 2003 Virtual ligand screening has proven to be a successful strategy in drug design. An in house-developed procedure (HierDock), a coarse grain docking method followed by a fine grain search procedure, was used to determine the binding site for sugars in the
Datta, Deepshikha
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Multi-class protein fold classification using a new ensemble machine learning approach. [PDF]
, 2003 Protein structure classification represents an important process in understanding the associations between sequence and structure as well as possible functional and evolutionary relationships.
Deville, Y, Gilbert, D, Tan, A
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Molecular Insights into the Flavivirus Replication Complex
Viruses, 2021 Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever viruses.
Kaïn van den Elsen +2 more
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The New High Resolution Crystal Structure of NS2B-NS3 Protease of Zika Virus
Viruses, 2017 Zika virus (ZIKV) is the cause of a significant viral disease affecting humans, which has spread throughout many South American countries and has also become a threat to Southeastern Asia.
Syed Lal Badshah +2 more
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Biomolecules, 2021 The SARS-CoV-2 non-structural protein (nsp) nsp10–nsp16 complex is essential for the 2′-O-methylation of viral mRNA, a crucial step for evading the innate immune system, and it is an essential process in SARS-CoV-2 life cycle.
Anwar Mohammad +5 more
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Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries [PDF]
, 2009 To facilitate the design of protein sequences with desired properties, simulation techniques have been developed to allow large portions of amino acid sequence space to be evaluated by computer.
Allen, Benjamin Daniel
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