Results 41 to 50 of about 18,387,865 (333)
Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes
Science Advances, 2021 Coronaviral nsp7+8 complexes follow species- and stoichiometry-specific assembly pathways determined by few amino acid changes. Coronaviruses infect many different species including humans.
Boris Krichel +12 more
semanticscholar +1 more source
Expression and purification of an adenylation domain from a eukaryotic nonribosomal peptide synthetase: Using structural genomics tools for a challenging target [PDF]
, 2010 Nonribosomal peptide synthetases (NRPSs) are large multimodular and multidomain enzymes that are involved in synthesising an array of molecules that are important in human and animal health.
Lee, TV +11 more
core +1 more source
The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?
Pathogens, 2016 Equine influenza virus remains a serious health and potential economic problem throughout most parts of the world, despite intensive vaccination programs in some horse populations.
Marta Barba, Janet M. Daly
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2021 Recent outbreak of deadly Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) urges the scientist to identify the potential vaccine or drug to control the disease. SARS-CoV-2 with its single stranded RNA genome (length ~ 30 kb) is enveloped with
Ram Kothandan +2 more
semanticscholar +1 more source
Coxsackievirus A6 Induces Cell Cycle Arrest in G0/G1 Phase for Viral Production
Frontiers in Cellular and Infection Microbiology, 2018 Recent epidemiological data indicate that outbreaks of hand, foot, and mouth disease (HFMD), which can be categorized according to its clinical symptoms as typical or atypical, have markedly increased worldwide. A primary causative agent for typical HFMD
Zengyan Wang +13 more
doaj +1 more source
Non-Contiguous Protein Recombination [PDF]
, 2013 Swapping sequence elements among related proteins can produce chimeric proteins with novel behaviors and improved properties such as enhanced stability. Although homologous mutations are much more conservative than random mutations, chimeras of distantly-
Smith, Matthew Alexander
core +1 more source
Acute Infection of Viral Pathogens and Their Innate Immune Escape
Frontiers in Microbiology, 2021 Viral infections can cause rampant disease in human beings, ranging from mild to acute, that can often be fatal unless resolved. An acute viral infection is characterized by sudden or rapid onset of disease, which can be resolved quickly by robust innate
Kul Raj Rai +7 more
doaj +1 more source
Baculovirus expression of pestivirus non-structural proteins
Journal of General Virology, 1992 Bovine viral diarrhoea virus (BVDV) belongs to the pestivirus group, a genus within the Flaviviridae family. It possesses a positive-sense ssRNA genome with a single large open reading frame (ORF) encoding about 4000 amino acids. Here we report the continuation of our studies of pestivirus protein biogenesis, involving expression from the viral non ...
M, Petric +4 more
openaire +2 more sources
Inherent structural disorder and dimerisation of murine norovirus NS1-2 protein [PDF]
, 2012 Human noroviruses are highly infectious viruses that cause the majority of acute, non-bacterial epidemic gastroenteritis cases worldwide. The first open reading frame of the norovirus RNA genome encodes for a polyprotein that is cleaved by the viral ...
Krause Kurt L. +17 more
core +1 more source