Results 11 to 20 of about 11,010,876 (174)
Development, characterization and comparisons of targeted and non-targeted metabolomics methods. [PDF]
PLoS ONE, 2018 The potential of a metabolomics method to detect statistically significant perturbations in the metabolome of an organism is enhanced by excellent analytical precision, unequivocal identification, and broad metabolomic coverage.
Anton Ribbenstedt +2 more
doaj +9 more sources
Non-targeted metabolomics in sport and exercise science [PDF]
Journal of Sports Sciences, 2017 Metabolomics incorporates the study of metabolites that are produced and released through physiological processes at both the systemic and cellular level.
Deighton, K +9 more
core +21 more sources
Isotopologue ratio normalization for non-targeted metabolomics [PDF]
Journal of Chromatography A, 2015 peer reviewedRobust quantification of analytes is a prerequisite for meaningful metabolomics experiments. In non-targeted metabolomics it is still hard to compare measurements across multiple batches or instruments. For targeted analyses isotope dilution
HILLER, Karsten +3 more
core +6 more sources
Non-targeted Metabolomics Reveals Metabolic Characteristics of Porcine Atretic Follicles [PDF]
Frontiers in Veterinary Science, 2021 Follicular atresia is one of the main factors limiting the reproductive power of domestic animals. At present, the molecular mechanisms involved in porcine follicular atresia at the metabolic level remain unclear.
Jiayuan Mo +7 more
doaj +3 more sources
Optimising a urinary extraction method for non-targeted GC–MS metabolomics
Scientific Reports, 2023 Urine is ideal for non-targeted metabolomics, providing valuable insights into normal and pathological cellular processes. Optimal extraction is critical since non-targeted metabolomics aims to analyse various compound classes.
Cara Olivier, Bianca Allen, Laneke Luies
doaj +3 more sources
Metabolites, 2023 Untargeted and targeted approaches are the traditional metabolomics workflows acquired for a wider understanding of the metabolome under focus. Both approaches have their strengths and weaknesses.
Susan S. Bird +2 more
core +2 more sources
Frontiers in Cardiovascular MedicineObjectiveThis study aimed to characterize serum metabolic profiles in hypertensive patients and investigate the regulatory role of tryptophan metabolism.MethodsWe employed an integrated metabolomics strategy that combined non-targeted screening with ...
Jing-wen Yue +7 more
doaj +2 more sources
In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics [PDF]
Pharmaceutics, 2021 Donepezil is a reversible acetylcholinesterase inhibitor that is currently the most commonly prescribed drug for the treatment of Alzheimer’s disease. In general, donepezil is known as a safe and well-tolerated drug, and it was not associated with liver ...
Sin-Eun Kim +9 more
doaj +3 more sources
Smart MedicineChronic suppurative otitis media (CSOM) is a leading cause of hearing loss and otorrhea, and when associated with cholesteatoma, it can pose a serious threat to patients' lives.
Lidan Hu +9 more
doaj +2 more sources
Non-Targeted Metabolomic Analysis of the Kombucha Production Process [PDF]
Metabolites, 2022 Kombucha is a traditional fermented beverage obtained from the transformation of sugared black tea by a community of yeasts and bacteria. Kombucha production recently became industrialized, but its quality standards remain poorly defined. Metabolomic analyses were applied using FT-ICR-MS to characterize the impacts of production phases and the type of ...
Tran, Thierry +8 more
openaire +4 more sources