Results 121 to 130 of about 720,330 (288)

Barriers to cervical cancer screening: a cross-sectional study of non-adherent Portuguese women

BMC Primary Care
Background Cervical cancer is preventable through effective screening programmes, yet adherence remains suboptimal in Portugal. This study aimed to explore the reasons for non-adherence to cervical cancer screening, including socio-demographic influences
Joana Margarida Costa, Ana Luís Pimentel, Inês Duarte, Ana Cristina Moreira, Joana Isabel Santos, Isabel Nazaré, Paulo Santos   +6 more
doaj   +1 more source

Elucidation of chemicals of emerging concern in placenta by non-targeted and suspect screening approaches

Emerging Contaminants
Over the past century, anthropic activities in industrialized countries have generated exposure to a vast array of environmental chemical families. Many of these may have harmful effects on human health, and xenobiotic exposure during the fetal period is
A. Domínguez-Liste, L. Espín-Moreno, M.O. Schweiss, A. Rodríguez-Carrillo, V. Mustieles, M.F. Fernandez, J. Arrebola, C. Freire, O. Ballesteros, J. Pérez-del-Palacio, F. Vela-Soria   +10 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging [PDF]

, 2012
Lung cancer is the leading cause of cancer deaths worldwide. Tobacco consumption is the primary cause of lung cancer, accounting for more than 85% 90% of all lung cancer deaths.
Rocha, E., Ferreira, J. P., Marques, F., Magalhães, M., Ferreira, J.   +4 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Advancing PFASs monitoring in food: from targeted SPE-LC-MS/MS to non-targeted QuEChERS-LC-HRMS approaches

Food Chemistry: X
Per- and polyfluoroalkyl substances (PFASs) are increasingly recognized as emerging contaminants, with some classified as persistent organic pollutants (POPs) and four recently regulated in food in the EU.
Cassandre Jeannot, Nicolas Macorps, Bruno Le Bizec, Julien Parinet, Gaud Dervilly   +4 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Screening programme 2014: Phosphites, selected PBT substances and non-target screening

, 2015
The occurrence and environmental risk of a number of phosphites and selected PBT substances are reported for wastewater effluents and leachates, as well as sediments and biota from Oslofjord and Lake Mjøsa. In addition a suspect and non-target screening approach was applied to approximatley half of the biota samples.
Thomas, Kevin, Schlabach, Martin, Langford, Katherine, Reid, Malcolm, Fjeld, Eirik, Øxnevad, Sigurd, Rundberget, Thomas, Bæk, Kine, Rostkowski, Pawel, Röhler, Laura, Borgen, Anders   +10 more
openaire   +2 more sources

Raw Data for Farmland’s Silent Threat: Non-targeted Screening of Micropollutants across Multimedia Domains

Farmland’s Silent Threat: Non-targeted Screening of Micropollutants across Multimedia ...
洋 丘 (18194623)
core   +1 more source