Results 101 to 110 of about 720,330 (288)

Breast screening in NSW, Australia: predictors of non-attendance and irregular attendance [PDF]

BreastScreen Australia provides free mammography services to women in the target age group of 50 to 69 years. The program uses a variety of measures to recruit women to the service and, subsequently, encourage them to screen at two year intervals. One of
Stephen Birch, Marion Haas, Minh Vu, Elizabeth Savage, Kees van Gool   +4 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A review of Non-targeted screening approaches to monitoring groundwater

, 2018
BAKER, AURORA. A review of non-targeted screening approaches to monitoring groundwater. (Under the direction of Dr. Elizabeth Nichols and Dr. Melanie Hedgespeth.) Monitoring groundwater for non-regulated contaminants has proven to be an experimental ...
Baker, Aurora
core  

Evaluation of volatile safety in children's play mats based on non-targeted screening and risk prioritization

Ecotoxicology and Environmental Safety
Given the widespread use of play mats and their close contact with children, it is crucial to identify potential chemical hazards associated with these products.
Shuang Liang, Haoyang Shi, Yinhui Yang, Qing Zhang, Zhijuan Wang, Qing Lv   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Development of a cost-effectiveness model for optimisation of the screening interval in diabetic retinopathy screening [PDF]

, 2015
BACKGROUND: The English NHS Diabetic Eye Screening Programme was established in 2003. Eligible people are invited annually for digital retinal photography screening.
Ramon Luengo-Fernandez, Stratton, Irene M, Sobha Sivaprasad, Scanlon, Peter H., Jason Oke, Gazis, Anastasios, Sivaprasad, Sobha, Stephen J Aldington, Luengo-Fernandez, Ramon, Aldington, Stephen J., Peter H Scanlon, Leal, Jose, Oke, Jason, Stratton, Irene M., Irene M Stratton, Jose Leal, Anastasios Gazis, Aldington, Stephen J, Scanlon, Peter H   +18 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Non-Targeted and Targeted Screening of Organic Contaminants in Honeybees’ Death Incidents in Greece: A Story Beyond Pesticides

Journal of Xenobiotics
Despite the undisputable ecosystem importance of honeybees, human activities have a substantial impact on their health. Since foraging is directly linked to a wide range of crops and bee-attracting flowers, plant protection products are at the forefront ...
Eirini Baira, Evangelia N. Tzanetou, Electra Manea-Karga, Kyriaki Machera, Konstantinos M. Kasiotis   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source