Results 151 to 160 of about 94,246 (299)

Metabolic Health Phenotypes Among Middle‐ to Older‐Aged Adults Living With and Without Obesity: Relationships With Hepatic Health Indicators

open access: yesHepatology Research, EarlyView.
We examined liver health indicators among obese and nonobese metabolic health phenotypes. In fully adjusted models, higher fatty liver index (FLI) scores and liver enzyme concentrations of gamma‐glutamyl transferase (GGT) and alanine aminotransferase (ALT) were associated with lower likelihood of metabolically healthy obese (MHO) and nonobese (MHNO ...
Grainne Dolan   +3 more
wiley   +1 more source

Steatotic Liver Disease: A Key Related Risk Factor in the Emergence of Metabolic Syndrome‐Related Disorders

open access: yesHepatology Research, EarlyView.
It is speculated that the onset of obesity‐related diseases follows the sequence of obesity → SLD → MetS‐related diseases. In this study, the contribution of SLD to each MetS‐related disease was large for T2D and hypertension and SLD contributed to the onset and new onset of the disease by the 7‐year follow‐up.
Yoshihiro Kamada   +6 more
wiley   +1 more source

The Hepatic Steatosis Diagnostic Performance Using Attenuation Imaging With the Magnetic Resonance Imaging‐Based Proton Density Fat Fraction as the Reference Standard: A Large, Prospective, Multicenter Cohort Study in Japan

open access: yesHepatology Research, EarlyView.
In a multicenter cohort of 1059 patients, attenuation imaging (ATI) showed good diagnostic performance and strong correlation with MRI‐PDFF, supporting its value as a noninvasive method for evaluating hepatic steatosis. ABSTRACT Background Attenuation imaging (ATI) is used for the noninvasive diagnosis of hepatic steatosis (HS) based on the ultrasound ...
Takashi Nishimura   +24 more
wiley   +1 more source

Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease

open access: green, 2015
Nishanth E. Sunny   +7 more
openalex   +1 more source

Machine Learning Approach Enables Highly Accurate Identification of At‐Risk Metabolic Dysfunction‐Associated Steatohepatitis

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim At‐risk metabolic dysfunction‐associated steatohepatitis (MASH), characterized by significant activity and fibrosis, increases the risk of liver complications. Liver stiffness measurement (LSM), commonly used to detect significant fibrosis, has limitations in terms of accessibility and performance in certain populations.
Masaya Sato   +15 more
wiley   +1 more source

Exploring a Subpopulation of MASLD Associated With New Onset of CKD Using Supervised Clustering Techniques

open access: yesHepatology Research, EarlyView.
The supervised clustering of metabolic dysfunction‐associated steatotic liver disease (MASLD) using a SHapley Additive exPlanations (SHAP)‐converted matrix reveals distinct subpopulations that improved risk stratification for new onset of chronic kidney disease (CKD).
Itaru Hosaka   +14 more
wiley   +1 more source

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