Results 191 to 200 of about 94,246 (299)

Effect of Citrus bergamia Supplementation on Body Composition in Humans: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity Reviews, EarlyView.
ABSTRACT This systematic review and meta‐analysis of randomized controlled trials (RCTs) was conducted to assess the effect of nutraceuticals containing Citrus bergamia on the management of obesity in adults by assessing measures related to obesity. We searched the following databases until October 2024: PubMed, Web of Science, Scopus, and the Cochrane
Carmelo Pujia   +8 more
wiley   +1 more source

Systematic Review of Loneliness and Social Isolation Interventions in Obesity and Obesity‐Related Complications

open access: yesObesity Reviews, EarlyView.
ABSTRACT People living with obesity and obesity‐related complications who are experiencing social isolation and loneliness (SIL) are at an increased risk of more disease‐specific complications, the presence of comorbidities, and mortality. Interventions targeting SIL may be of benefit in this population, though research in this field is limited.
Ghada Alsultany   +3 more
wiley   +1 more source

Efficacy of Weight‐Lowering Agents on Fat Distribution: A Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity Reviews, EarlyView.
ABSTRACT Background Pharmacotherapy offers a potential solution for individuals with overweight and obesity to decrease their body weight. However, there is limited knowledge of the effects of antiobesity agents on the distribution of body fat. Methods The PubMed, Embase, and Cochrane Library databases were reviewed for randomized controlled trials ...
Xiuqi Qiao   +4 more
wiley   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes

open access: yesGlia, Volume 74, Issue 3, March 2026.
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve   +5 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

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