Results 61 to 70 of about 94,246 (299)

The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)

Lipids in Health and Disease, 2010
Nonalcoholic fatty liver disease is increasingly regarded as a hepatic manifestation of metabolic syndrome, and the severity of nonalcoholic fatty liver disease seems to increase in parallel with other features of metabolic syndrome.
Bengmark Stig, Liu Qing, Qu Shen
doaj   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

ASSOCIATION OF ANTHROPOMETRIC AND BIOCHEMICAL PARAMETERS WITH NONALCOHOLIC FATTY LVER DISEASE

Pakistan Armed Forces Medical Journal, 2019
Objective: To study the association of anthropometric and biochemical parameters with nonalcoholic fatty liver disease (NAFLD) diagnosed on ultrasonography (USG). Study Design: Cross sectional analytical study.
Muhammad Usman Munir, Omar Iqbal, Romana Anwar, Juwayria Omar   +3 more
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Nonalcoholic Fatty Liver Disease and Continuous Metabolic Syndrome in Adolescents with Overweight/Obesity

Acta Médica Portuguesa
Introduction: Nonalcoholic fatty liver disease is the leading cause of pediatric chronic liver disease. Although nonalcoholic fatty liver disease is closely associated with obesity, its relationship with metabolic syndrome in children is not fully ...
Sofia Ferreira, Joana Mendes, Daniela Couto, Dário Ferreira, Carla Rêgo   +4 more
doaj   +1 more source

Nonalcoholic Fatty Liver Disease-Related Chronic Kidney Disease

Canadian Journal of Gastroenterology and Hepatology, 2020
Nonalcoholic fatty liver disease has become the main concern of hepatologists around the world and the main research topic for identifying effective and safe therapy.
Camelia Cojocariu, Ana-Maria Singeap, Irina Girleanu, Stefan Chiriac, Cristina M. Muzica, Catalin Victor Sfarti, Tudor Cuciureanu, Laura Huiban, Carol Stanciu, Anca Trifan   +9 more
doaj   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

NONALCOHOLIC FATTY LIVER DISEASE (NAFLD) FREQUENCY IN DIABETES MELLITUS (DM) TYPE –II PATIENTS

FUUAST Journal of Biology, 2021
The purpose of this study was to determine the frequency of nonalcoholic fatty liver disease (NAFLD) in the patients with diabetes mellitus (DM) type-II.
MUHAMMAD YAHYA AFZAL, HAFIZ SOHAIL ANJUM, UZMA NASIM SIDDIQUI, Saman Shaihd   +3 more
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Effect of Korean Red Ginseng in chronic liver disease

Journal of Ginseng Research, 2017
Chronic liver disease, one of the most common diseases, typically arises from nonalcoholic fatty liver disease, alcoholic liver disease, chronic viral hepatitis, or hepatocellular carcinoma.
Tae Young Park, Meegun Hong, Hotaik Sung, Sangyeol Kim, Ki Tae Suk   +4 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Research progress on the relationship between food types and dietary patterns and nonalcoholic fatty liver disease

Huli yanjiu, 2021
It reviewed the effects of different foods types and dietary patterns on nonalcoholic fatty liver disease.It was pointed out that weight control was the cornerstone of the treatment of nonalcoholic fatty liver disease.Zoned diet weight watchers diet ...
CHEN Fang, HU Hui, AI Yating, TAN Hongqiong   +3 more
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