Results 41 to 50 of about 2,835,571 (143)

Residue-Specific Incorporation of the Non-Canonical Amino Acid Norleucine Improves Lipase Activity on Synthetic Polyesters

Frontiers in Bioengineering and Biotechnology, 2022
Environmentally friendly functionalization and recycling processes for synthetic polymers have recently gained momentum, and enzymes play a central role in these procedures.
Karolina Haernvall, Patrik Fladischer, Patrik Fladischer, Heidemarie Schoeffmann, Sabine Zitzenbacher, Tea Pavkov-Keller, Tea Pavkov-Keller, Tea Pavkov-Keller, Tea Pavkov-Keller, Karl Gruber, Karl Gruber, Karl Gruber, Michael Schick, Motonori Yamamoto, Andreas Kuenkel, Doris Ribitsch, Doris Ribitsch, Georg M. Guebitz, Georg M. Guebitz, Birgit Wiltschi, Birgit Wiltschi, Birgit Wiltschi   +21 more
doaj   +1 more source

Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant

Journal of Nucleic Acids, 2010
Base analogs are powerful antimetabolites and dangerous mutagens generated endogenously by oxidative stress, inflammation, and aberrant nucleotide biosynthesis.
Irina S.-R. Waisertreiger, Miriam R. Menezes, James Randazzo, Youri I. Pavlov   +3 more
doaj   +1 more source

Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity

mBio, 2017
Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying transcription activators that drive the transcriptional response to amino acid limitation.
Ivaylo P. Ivanov, Jiajie Wei, Stephen Z. Caster, Kristina M. Smith, Audrey M. Michel, Ying Zhang, Andrew E. Firth, Michael Freitag, Jay C. Dunlap, Deborah Bell-Pedersen, John F. Atkins, Matthew S. Sachs   +11 more
doaj   +1 more source

AMINO ACID DIGESTIBILITIES OF PALM KERNEL MEAL IN POULTRY [PDF]

, 2008
Palm kernel meal (PKM) is produced in large quantities in many parts of the world. Problems associated with PKM are due to their high fibre content, imbalanced amino acid ratios, the possibility of Maillard products and their own physical ...
Kumar, A, Dingle, J, Sundu, B
core   +1 more source

Noncanonical altPIDD1 protein: unveiling the true major translational output of the PIDD1 gene

Life Science Alliance
This research uncovers PIDD1 as a dual-coding gene, revealing a previously unknown protein, altPIDD1, as the primary product with higher expression and cytoskeletal interactions.
Frédérick Comtois, Jean-François Jacques, Lenna Métayer, Wend Yam DD Ouedraogo, Aïda Ouangraoua, Jean-Bernard Denault, Xavier Roucou   +6 more
doaj   +1 more source

Acute Synthesis of CPEB Is Required for Plasticity of Visual Avoidance Behavior in Xenopus

Cell Reports, 2014
Neural plasticity requires protein synthesis, but the identity of newly synthesized proteins generated in response to plasticity-inducing stimuli remains unclear. We used in vivo bio-orthogonal noncanonical amino acid tagging (BONCAT) with the methionine
Wanhua Shen, Han-Hsuan Liu, Lucio Schiapparelli, Daniel McClatchy, Hai-yan He, John R. Yates III, Hollis T. Cline   +6 more
doaj   +1 more source

Metabolic Implications of Using BioOrthogonal Non-Canonical Amino Acid Tagging (BONCAT) for Tracking Protein Synthesis

Frontiers in Microbiology, 2020
BioOrthogonal Non-Canonical Amino acid Tagging (BONCAT) is a powerful tool for tracking protein synthesis on the level of single cells within communities and whole organisms.
Katherine F. Steward, Brian Eilers, Brian Tripet, Amanda Fuchs, Michael Dorle, Rachel Rawle, Berliza Soriano, Narayanaganesh Balasubramanian, Valérie Copié, Valérie Copié, Brian Bothner, Brian Bothner, Roland Hatzenpichler, Roland Hatzenpichler, Roland Hatzenpichler   +14 more
doaj   +1 more source

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells

, 2014
Background/aims: human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions. Culture at low oxygen
Christensen, David R., David R. Christensen, Calder, Philip C., Houghton, Franchesca D., Philip C. Calder, Franchesca D. Houghton   +5 more
core   +1 more source

Comparative functional genomics of amino acid metabolism of lactic acid bacteria [PDF]

, 2009
The amino acid metabolism of lactic acid bacteria used as starters in industrial fermentations has profound effects on the quality of the fermented foods.
Pastink, M.I.
core  

Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo [PDF]

, 2013
N-methyl-d-aspartate receptor (NMDAR) activation can initiate changes in synaptic strength, evident as long-term potentiation (LTP), and is a key molecular correlate of memory formation.
Kerry L. Spear, Seth C. Hopkins, Hopkins, Seth C., David C. Spanswick, Heffernan, Michele L. R., Campbell, Una C., Ross D. Jeggo, Spear, Kerry L., Varney, Mark A., Michele L. R. Heffernan, Thomas H. Large, Spanswick, David C., Jeggo, Ross D., Mark A. Varney, Large, Thomas H., Una C. Campbell   +15 more
core   +1 more source