Results 71 to 80 of about 1,008,618 (142)

Restoration of EMX2 expression using an adenoviral delivery system suppressed gastric cancer cell proliferation in vitro.

, 2013
(A) MTS assay.
Zhao Chen (92571), Yi Zhang (9093), Qing Sheng (50321), Fang Zhang (197215), Minli Mo (306430), Hang Mu (133804), Xiu-Yi Zhi (306431), Jie Li (15030), Hui Li (32376), Biao He (1833), Hai-Meng Zhou (133815), Zhe Chen (196097)   +11 more
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Successful expression of human factor IX following repeat administration of adenoviral vector in mice.

, 1996
Adenoviral vectors can direct high-level expression of a transgene, but, due to a host immune response to adenoviral antigens, expression is of limited duration, and repetitive administration has generally been unsuccessful.
Sands, M, High, K A, Hagstrom, J. Nathan, MD, MHCM, Walter, J, You, Q   +4 more
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Adenoviral vectors for gene therapy

Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy.
San Martín, Carmen, Gallardo, José, Martínez, Marta, Condezo, Gabriela N.   +3 more
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Overexpressed Apurinic/Apyrimidinic Endonuclease/Redox Effector Factor-1 Using Adenoviral Vector Inhibits Induction of Neuronal Cell Death after Transient Ischemic Stroke in Mice [PDF]

, 2008
Background: Despite the correlation between changes in the levels of apurinic/apyrimidinic endonuclease/redox effector factor-1 (APE/Ref-1), the DNA base excision repair protein, and ischemic neuronal damage, no studies have addressed the question of ...
김현우, 김경환, 김현정, 조경주, 이병인   +4 more
core  

Progress in Adenoviral Capsid-Display Vaccines

, 2018
Adenoviral vectored vaccines against infectious diseases are currently in clinical trials due to their capacity to induce potent antigen-specific B- and T-cell immune responses. Heterologous prime-boost vaccination with adenoviral vector and, for example,
Marija Vujadinovic, Jort Vellinga
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Danio rerio as model organism for adenoviral vector evaluation [PDF]

, 2019
Viral vector use is wide-spread in the field of gene therapy, with new clinical trials starting every year for different human pathologies and a growing number of agents being approved by regulatory agencies.
Guerra-Varela, J. (Jorge), Ricobaraza, A. (Ana), Gulías, P. (Paola), Sánchez, L. (Laura), Vales, A. (África), Gonzalez-Aparicio, M. (Manuela), Hernandez-Alcoceba, R. (Rubén), González-Aseguinolaza, G. (Gloria)   +7 more
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Establishment of a Parvovirus B19 NS1-Expressing Recombinant Adenoviral Vector for Killing Megakaryocytic Leukemia Cells

, 2019
Adenoviral viral vectors have been widely used for gene-based therapeutics, but commonly used serotype 5 shows poor transduction efficiency into hematopoietic cells.
Peng Xu, Yi Li, Xiaomei Wang, Jianming Qiu   +3 more
core   +1 more source

Developing the next-generation of adenoviral vector vaccines

The COVID-19 pandemic saw the first extensive use of adenoviral vector vaccines, with over 3 billion doses produced during the first year of the pandemic alone and an estimated 6 million lives saved.

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Toxicity of pegylated helper-dependent adenoviral vectors in non-human primates [PDF]

, 2008
Leggiero, Eleonora
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