, 2001 Objectives: Conditions for ex vivo gene transfer to the transplanted heart were studied in a model of syngeneic abdominal heterotopic heart transplantation in the rat.
J. Yap +4 more
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Helper-dependent adenoviral gene therapy mediates long-term correction of the clotting defect in the canine hemophilia A model [PDF]
, 2006 Adenoviral vector-mediated gene therapy might have potential for long-term correction of the monogenic disease hemophilia ...
McCORMACK, W. M. +7 more
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Transfer of TALEN sequences into adenoviral vectors and validation of TALEN function.
, 2013 A. The left and right TALEN sequences described in Figure 1 were transferred into an adenoviral destination vector, pAd/PL-DEST, by Gateway® LR recombination. B-D, Example of transduction of Ddx3x TALEN adenoviruses into mouse Neuro-2A cells.
Xin Huang (11077) +4 more
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Adenovirus-Mediated Gene Transfer of Viral Interleukin-10 Inhibits the Immune Response to Both Alloantigen and Adenoviral Antigen [PDF]
, 1997 Overview summary Adenoviral vectors are efficient for in vivo delivery of genes to a wide variety of tissue types, whereas the duration of expression is limited by the potent adenovirus-specific immune response directed to the infected cell.
Ding, Yaozhong +11 more
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, 2007 We aimed to increase the efficiency of adenoviral vectors by limiting adenoviral spread from the target site and reducing unwanted host immune responses to the vector. We complexed adenoviral vectors with DDAB-DOPE liposomes to form adenovirus-liposomal (
Tsokos, Maria +6 more
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Estudo da resposta imune contra o antígeno Gag de HIV-1 no trato genital feminino murino induzida pela administração de adenovírus recombinantes [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2010AIDS é um dos principais problemas de saúde pública atuais e acredita-se que a epidemia somente será controlada com uma vacina capaz
Haut, Larissa Herkenhoff
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Adenoviral vector-mediated rescue of the OMP-null phenotype in vivo
, 2000 The use of gene deletion by homologous recombination to determine gene or protein function has wide application in vertebrate neurobiology. An ideal complement to gene deletion would be subsequent gene replacement to demonstrate re-acquisition of ...
Richards, LJ +11 more
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Avaliação de células da imunidade inata do trato genital de camundongos imunizados por via intravaginal com uma vacina de adenovírus recombinante [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2009Embora adenovírus (Ad) humano do sorotipo 5 tenha sido utilizado como vetor vacinal contra inúmeras doenças infecciosas, a ...
Lanza, Silvia Regina
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Adenoviral vector-based vaccine against enterovirus infection
[[abstract]]The present invention relates to a recombinant adenoviral vector for generating immunity against enterovirus infection. In one embodiment, the recombinant adenoviral vector of the invention comprises an expression cassette encoding a PI ...
Chow, YH;Tsou, YL;Chong, PCS
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