Results 101 to 110 of about 1,436,982 (204)
Abstract Objective This study was undertaken to estimate the prevalence and characterize the semiology of co‐occurring functional/dissociative seizures (FDSs) and identify clinical features potentially associated with the development of video‐electroencephalography (video‐EEG)‐diagnosed FDSs in patients with idiopathic generalized epilepsy (IGE ...
Javier Peña‐Ceballos +13 more
wiley +1 more source
Chapter Forty-Six - Nonmotor Features in Atypical Parkinsonism
Atypical parkinsonism (AP) comprises mainly multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD), which are distinct pathological entities, presenting with a wide phenotypic spectrum.
Stamelou, M, Bhatia, KP
core +1 more source
Abstract Pediatric drug‐resistant epilepsy (DRE) remains a significant clinical challenge, with few effective pharmacological options. This European multicenter retrospective study assessed the real‐world efficacy, tolerability, and retention of off‐label cenobamate (CNB) in 108 children and adolescents with DRE (median age: 13.83 years, range 3.9–19.8)
Konstantin L. Makridis +14 more
wiley +1 more source
Nonmotor symptoms in Parkin gene-related parkinsonism.
Contains fulltext : 89859.pdf (Publisher’s version ) (Open Access)The aim of the study was to explore the prevalence and differences of nonmotor symptoms (NMSs) in patients with young-onset Parkinson's disease (YOPD) with and without ...
Kagi, G. +17 more
core +1 more source
Emergence of nonmotor symptoms as the focus of research and treatment of Parkinson's disease: Introduction to the special section on nonmotor dysfunctions in Parkinson's disease [PDF]
Parkinson's disease (PD) is traditionally characterized by the cardinal motor symptoms of tremor, rigidity, slowness of movement, and impairments of posture, gait, and balance.
Cronin-Golomb, Alice
core +1 more source
Loss of α5‐nAChRs drives age‐dependent, sex‐specific behavioral alterations, with females showing early cognitive deficits and males a progressive decline. These findings identify α5‐nAChRs as key regulators of neural circuit maturation and underscore the critical importance of incorporating sex as a biological variable in preclinical research ...
Danai Papavranoussi Daponte +3 more
wiley +1 more source
Non-motor symptoms in parkinson’s disease [PDF]
<p>The goal of the research was to investigate some non-motor disorders at patients with Parkinson disease (PD) and to determine their relations to the main manifestations of the disease. 68 patients with PD without dementia were studied.
Baidina T.V., Torgan T.I.
doaj
Parkinson's disease (PD) is characterized not only by typical motor symptoms, but also by nonmotor symptoms in the early stages. In addition to the loss of dopaminergic (DAergic) neurons, progressive degenerations of noradrenergic (NA) and serotonergic ...
Yong Li +6 more
doaj +1 more source
Association Between Plasma Phosphorylated Tau‐217 and Cognition in Parkinson's Disease
Abstract Background Alzheimer's disease (AD) co‐pathology contributes to dementia in PD, but its role in earlier cognitive impairment remains uncertain. Objective To determine if p‐tau217, a biomarker of early AD, is associated with cognitive impairment in PD.
Trycia Kouchache +10 more
wiley +1 more source

