Results 131 to 140 of about 463,256 (209)

DeepAden: an explainable machine learning method for predicting the substrate specificity of nonribosomal peptide synthetases. [PDF]

Nucleic Acids Res
Huang J, Ge L, Wu Y, Tian Y, Wu J, Gao Q, Li P, Meng S, Zhang H, Qin Z.   +9 more
europepmc   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram-Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach. [PDF]

Adv Sci (Weinh)
Chen K, Liang J, Wu Y, Xu J, Liu Y, Wang W, Jiang X, Gao B, Wang Y, Jiang H.   +9 more
europepmc   +1 more source

Structure of a stand-alone homodimeric nonribosomal peptide synthetase condensation domain reveals occlusion of the canonical carrier-protein interface. [PDF]

J Biol Chem
Singh J, Grant TD, Gulick AM.
europepmc   +1 more source

Paenitracins, a novel family of bacitracin-type nonribosomal peptide antibiotics produced by plant-associated <i>Paenibacillus</i> species. [PDF]

mSystems
Machushynets NV, Elsayed SS, Du C, Lysenko V, de la Cruz M, Sanchez P, Genilloud O, Martin NI, Liles MR, van Wezel GP.   +9 more
europepmc   +1 more source

Identification of the lipodepsipeptide selethramide encoded in a giant nonribosomal peptide synthetase from a Burkholderia bacterium. [PDF]

Proc Natl Acad Sci U S A, 2023
Romanowski SB, Lee S, Kunakom S, Paulo BS, Recchia MJJ, Liu DY, Cavanagh H, Linington RG, Eustáquio AS.   +8 more
europepmc   +1 more source

Structural Basis for a Scaffolding Role of the COM Domain in Nonribosomal Peptide Synthetases. [PDF]

Angew Chem Int Ed Engl
Diecker J, Hermanns B, Rüschenbaum J, Rasche R, Dörner W, Schröder A, Kümmel D, Mootz HD.   +7 more
europepmc   +1 more source

Teicoplanin Nonribosomal Peptide Synthetase Is Unable to Incorporate Alpha-Ketoacid Building Blocks. [PDF]

Biochemistry
Ratnayake MS, Jian X, Tailhades J, Challis GL, Hansen MH, Lewandowski JR, Cryle MJ.   +6 more
europepmc   +1 more source

Degradation of Nonribosomal Peptide Synthetase Megasynthetases SrfAA and SrfAB by Acyldepsipeptide-Activated ClpP in Bacillus Subtilis. [PDF]

Chembiochem
Ishikawa F, Uchida C, Ohnishi R, Imai T, Tanabe G.   +4 more
europepmc   +1 more source

Biosynthesis of Antifungal Solanimycin May Involve an Iterative Nonribosomal Peptide Synthetase Module. [PDF]

ACS Chem Biol, 2023
Murphy AC, Corney M, Monson RE, Matilla MA, Salmond GPC, Leeper FJ.   +5 more
europepmc   +1 more source

Biosynthesis of Antituberculosis Antibiotic Capreomycin Involves a <i>trans</i>-Iterative Adenylation Domain within the Nonribosomal Peptide Synthetase Machinery. [PDF]

Org Lett
Lai YT, Peng CY, Liao HT, Hsiao PY, Hsieh CK, Luo YR, Huang SC, Wang YL, Ma T, Chen YR, Kuo YM, Lin YC, Chu J, Chang CY.   +13 more
europepmc   +1 more source