Results 111 to 120 of about 463,256 (209)
New Microbes and New Infections, 2017 We report the draft genome sequence of Haloferax alexandrinus strain Arc-hr (CSUR P798), isolated from the human gut of a 10-year-old Amazonian individual. Its 3 893 626 bp genome exhibits a 66.00% GC content.
S. Khelaifia +3 more
doaj +1 more source
, 2016 A facile genetic methodology in the filamentous fungus Aspergillus nidulans allowed the exchange of various domains in nonribosomal peptide synthase (NRPS)-like enzymes from Aspergillus terreus.
Clay C. C. Wang (313310) +2 more
core +1 more source
Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection.
PLoS Pathogens, 2007 Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for virulence, but non-existent in humans, presenting a rare opportunity to strategize therapeutically against this pathogen.
Markus Schrettl +9 more
doaj +1 more source
ANTI-BACTERIAL PROPERTY OF A CORAL-ASSOCIATED BACTERIUM Bacillus sp. AGAINST CORAL PATHOGENIC [PDF]
, 2006 Marine organisms such as corals are frequently colonized by bacteria that may be pathogenic to them. One of the means by which they are able to combat microbial attack is by chemical defense.
Radjasa, Ocky Karna, Sabdono, Agus
core +1 more source
Enhancing Nonribosomal Peptide Biosynthesis in Filamentous Fungi [PDF]
, 2016 Filamentous fungi are historically known as rich sources for production of biologically active natural products, so-called secondary metabolites. One particularly pharmaceutically relevant chemical group of secondary metabolites is the nonribosomal peptides synthesized by nonribosomal peptide synthetases (NRPSs).
Alexandra A, Soukup +2 more
openaire +2 more sources
, 2016 Analysis of naphthyridinomycin gene cluster revealed that this antibiotic is generated by nonribosomal peptide synthetase (NRPS) machinery. However, four modules encoded by two genes do not correspond with the structural units in the final product ...
Yue Zhang (30585) +7 more
core +1 more source
Identification and structure of nonribosomal peptide synthetases in Cochliobolus miyabeanus TG12bL2.
, 2016 Identification and structure of nonribosomal peptide synthetases in Cochliobolus miyabeanus TG12bL2.
Juan J. Gutierrez-Gonzalez (131256) +6 more
core +1 more source
Reprogramming Promiscuous Nonribosomal Peptide Synthetases for Production of Specific Peptides
, 2019 Pairs of docking domains (DDs) mediate the selective interations between adjacent nonribosomal peptide synthetases (NRPSs) to form defined protein–protein interactions resulting in defined peptide sequences.
Bode, H. +5 more
core +1 more source
Mechanistic Insights Into the Biosynthesis of Pseurotin A in Aspergillus fumigatus
Small StructuresThe biosynthesis of pseurotin A, a fungal metabolite with antibiotic and immunosuppressive properties, involves a group of enzymes, including a polyketide‐nonribosomal peptide synthase (PKS‐NRPS), PsoA, and a bifunctional enzyme, PsoF. PsoA consists of a
Lei Sun +5 more
doaj +1 more source
A Fungal Nonribosomal Peptide Synthetase Module that can Synthesize Thiopyrazines
, 2016 A nonribosomal peptide synthetase-like enzyme (NRPS325) from Aspergillus terreus was reconstituted in vitro and was shown to synthesize thiopyrazines using an unprecedented mechanism. Substrate promiscuity of NRPS325 toward different amino acids and free
Neil Garg (2216656) +5 more
core +1 more source