Results 161 to 170 of about 18,126 (202)

A trans-activating transduction peptide fused nanobody targeting viral nonstructural protein NS4B inhibits bovine viral diarrhea virus replication. [PDF]

Front Immunol
Zhao B, Lv Z, Fan W, Zhang Y, Wei S, Fang J, Huang N, Chen X, Wang L, Qi X.   +9 more
europepmc   +1 more source

Mass Spectrometry-Based Proteomic Analysis of Porcine Reproductive and Respiratory Syndrome Virus NSP9 Protein with Host Proteins. [PDF]

Animals (Basel)
Wen W, Liu Y, Wang W, Zhu Z, Li X.
europepmc   +1 more source

Attenuation Profile and Molecular Characterization of a High-Passaged Attenuated Getah Virus Strain. [PDF]

Transbound Emerg Dis
Chen J, Wu H, Lin A, Miu X, Li Y, Zhu Q, Lu Y, Zhang X, Zhang Z, Li K, Li P, Yang T, Hu Y.   +12 more
europepmc   +1 more source

Correction for Wu et al., "Enterovirus A71 Promotes Exosome Secretion by the Nonstructural Protein 3A Interacting with Rab27a". [PDF]

Microbiol Spectr
Wu J, Zhao Y, Chen Q, Chen Y, Gu J, Mao L.   +5 more
europepmc   +1 more source

Grass carp Trim47 restricts GCRV infection via SPRY domain-mediated autophagic degradation of nonstructural proteins and disruption of viral inclusion bodies. [PDF]

Front Immunol
Yan W, Chen Y, Yan D, Zhang J, Chang MX.
europepmc   +1 more source

Viral protease-mediated polyprotein processing in human astroviruses

Noyvert D, Neves LX, Fominykh K, Hankinson J, Lindsey G, Lulla A, Emmott E, Lulla V.   +7 more
europepmc   +1 more source

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Mechanism of zinc ejection by disulfiram in nonstructural protein 5A

Physical Chemistry Chemical Physics, 2021
Hepatitis C virus (HCV) is a notorious member of the Flaviviridae family of enveloped, positive-strand RNA viruses.
Ashfaq Ur Rehman, Guodong Zhen, Bozitao Zhong, Duan Ni, Jiayi Li, Abdul Nasir, Moustafa T. Gabr, Humaira Rafiq, Abdul Wadood, Shaoyong Lu, Jian Zhang, Hai-Feng Chen   +11 more
openaire   +2 more sources

SUMOylation of nonstructural 5A protein regulates hepatitis C virus replication

Journal of Viral Hepatitis, 2014
SummaryViruses exploit cellular SUMOylation machinery to favour their own propagation. We show that NS5A is a target protein of small ubiquitin‐like modifier (SUMO) and is SUMOylated at lysine residue 348. We demonstrated that SUMOylation increased protein stability of NS5A by inhibiting ubiquitylation, and SUMOylation was also required for protein ...
H S, Lee, Y S, Lim, E M, Park, S H, Baek, S B, Hwang   +4 more
openaire   +2 more sources

Hepatitis C virus nonstructural region 5A protein is a potent transcriptional activator

Journal of Virology, 1997
The hepatitis C virus (HCV) nonstructural region 5A (NS5A) protein, without its 146 amino-terminal amino acids and fused to the DNA-binding domain of GAL4, strongly activates transcription in yeast and human hepatoma cells. Transcriptional activation by the HCV NS5A protein may play a role in viral replication and hepatocarcinogenesis.
N, Kato, K H, Lan, S K, Ono-Nita, Y, Shiratori, M, Omata   +4 more
openaire   +2 more sources

Analysis for codon usage bias in membrane anchor of nonstructural protein 5A from BVDV

Journal of Basic Microbiology, 2023
AbstractThe nonstructural protein 5A (NS5A) of the bovine viral diarrhea virus (BVDV) is a monotopic membrane protein. This protein can anchor to the cell membrane by an in‐plane amphipathic ⍺‐helix, which participates in the viral replication complex.
Mingyang Gao, Xuanye Yang, Yuhu Wu, Jinqian Wang, Xinyan Hu, Zhongren Ma, Jian‐hua Zhou   +6 more
openaire   +2 more sources