Results 171 to 180 of about 13,111 (197)
Some of the next articles are maybe not open access.
Journal of Viral Hepatitis, 2011
Summary. We identified heat shock protein 72 (Hsp72) as a host factor that was differentially expressed in cells expressing nonstructural 5A (NS5A) protein. To investigate how NS5A modulates Hsp72 in hepatitis C virus (HCV) life cycle, we examined the role of Hsp72 in HCV replication and virus production. NS5A specifically interacted with Hsp72.
Y S, Lim +5 more
openaire +2 more sources
Summary. We identified heat shock protein 72 (Hsp72) as a host factor that was differentially expressed in cells expressing nonstructural 5A (NS5A) protein. To investigate how NS5A modulates Hsp72 in hepatitis C virus (HCV) life cycle, we examined the role of Hsp72 in HCV replication and virus production. NS5A specifically interacted with Hsp72.
Y S, Lim +5 more
openaire +2 more sources
HCV Inhibition Mediated Through the Nonstructural Protein 5A (NS5A) Replication Complex
2012Abstract Chronic infection by hepatitis C virus (HCV) results in increased risk for cirrhosis and hepatocellular carcinoma. Current treatments of HCV infection use inhibitors of HCV NS3 protease in combination with pegylated interferon α and ribavirin resulting in approximately 70% cure rates.
Robert Hamatake +2 more
openaire +1 more source
Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2
Proceedings of the National Academy of Sciences of the United States of America, 2021Jingjing Pei +2 more
exaly

