Results 181 to 190 of about 1,587,098 (210)

Inhibitors of the Structural and Nonstructural Proteins of Alphaviruses

ACS Infectious Diseases
The Alphavirus genus includes viruses that cause encephalitis due to neuroinvasion and viruses that cause arthritis due to acute and chronic inflammation. There is no approved therapeutic for alphavirus infections, but significant efforts are ongoing, more so in recent years, to develop vaccines and therapeutics for alphavirus infections.
Damilohun Samuel Metibemu, John Adeolu Falode, Ifedayo Víctor Ogungbe   +2 more
exaly   +3 more sources

Structural and nonstructural proteins of a rabbit parvovirus

Journal of Virology, 1983
The structural and nonstructural polypeptides of a rabbit parvovirus (RPV) (F-7-9 strain) were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The virion contained three polypeptide components, A (molecular weight, 96,000), B (85,000), and C (75,000).
Y, Matsunaga, S, Matsuno
openaire   +2 more sources

Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

Journal of Virology, 1991
The cleavages at the junctions of the flavivirus nonstructural (NS) proteins NS2A/NS2B, NS2B/NS3, NS3/NS4A, and NS4B/NS5 share an amino acid sequence motif and are presumably catalyzed by a virus-encoded protease. We constructed recombinant vaccinia viruses expressing various portions of the NS region of the dengue virus type 4 polyprotein.
B, Falgout, M, Pethel, Y M, Zhang, C J, Lai   +3 more
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The Nonstructural Proteins of Paramyxoviruses

1991
This chapter describes properties of the paramyxovirus genes and their mRNAs which encode polypeptides known as nonstructural proteins. The designation nonstructural is used here in a loose sense to describe a virus-encoded polypeptide that is synthesized in virus-infected cells but is greatly underrepresented in or absent from purified virions.
Robert A. Lamb, Reay G. Paterson
openaire   +1 more source

Cloning and inducible synthesis of poliovirus nonstructural proteins

Gene, 1992
The poliovirus nonstructural protein-encoding genes have been cloned and expressed in Escherichia coli using the inducible system described by Studier and Moffat [J. Mol. Biol. 189 (1986) 113-130] and Studier [J. Mol. Biol. 219 (1991) 37-44]. The two genes encoding the poliovirus proteases, 2Apro and 3Cpro, were cloned together with their flanking ...
J, Lama, R, Guinea, F, Martinez-Abarca, L, Carrasco   +3 more
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WITHDRAWN: The nonstructural protein-1 of influenza virus A

The International Journal of Biochemistry & Cell Biology, 2008
This article has been retracted; please see Elsevier Policy on Article Withdrawal: http://www.elsevier.com/locate/withdrawalpolicy This article has been retracted at the request of the Editor-in-Chief of The International Journal of Biochemistry and Cell Biology, as the authors have plagiarised sections of several other papers that had been previously ...
Hua, Jiang, Chong, Xu, Yanbing, Zhang, Guoqiang, Chen, Yongtao, Xiao   +4 more
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In vivo interactions among rotavirus nonstructural proteins

Archives of Virology, 1998
The rotavirus genome encodes six nonstructural (NS) proteins, five of which (NSP1, NSP2, NSP3, NSP5, and NSP6) have been suggested to be involved in a variety of events, such as genome replication, regulation of gene expression, and gene assortment. These NS proteins have been found to be associated with replication complexes that are precursors of the
R A, González, M A, Torres-Vega, S, López, C F, Arias   +3 more
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Expression and Processing of Nonstructural Proteins of the Human Astroviruses

1998
The human astroviruses (HAst) are increasingly recognized as an important cause of gastroenteritis. These viruses contain a 6.8-kb positive-sense, single-stranded RNA molecule that is infectious when transfected into permissive cells. The HAst gene 1 is composed of two open reading frames (ORFs 1a and 1b) connected by a ribosomal frameshift.
C A, Gibson, J, Chen, S A, Monroe, M R, Denison   +3 more
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Structural Organisation of the Rotavirus Nonstructural Protein NSP5

Journal of Molecular Biology, 2011
Rotavirus is one of the leading agents of gastroenteritis worldwide. During infection, viral factories (viroplasms) are formed. The rotavirus nonstructural proteins NSP5 and NSP2 are the major building blocks of viroplasms; however, NSP5 function and organisation remain elusive. In this report, we present a structural characterisation of NSP5.
Davy, Martin, Malika, Ouldali, Julie, Ménétrey, Didier, Poncet   +3 more
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Structural and Nonstructural Adenovirus Proteins

1984
The adenovirus family comprises a large number of serotypes (species) of both human and animal origin. The human serotypes have been studied most intensively, and this review considers almost exclusively proteins that are produced as the result of a human adenovirus infection.
openaire   +1 more source