Results 61 to 70 of about 19,166 (219)

T-Cell Exhaustion in Mycobacterium tuberculosis and Nontuberculous Mycobacteria Infection: Pathophysiology and Therapeutic Perspectives

Microorganisms, 2021
Immune exhaustion is a condition associated with chronic infections and cancers, characterized by the inability of antigen-specific T cells to eliminate the cognate antigen. Exhausted T cells display a peculiar phenotypic profile and exclusive functional
Andrea Lombardi, Simone Villa, Valeria Castelli, Alessandra Bandera, Andrea Gori   +4 more
doaj   +1 more source

Emerging role of metagenomic next‐generation sequencing in infectious disease diagnostics: Clinical integration and future directions

mLife, Volume 5, Issue 2, Page 148-163, April 2026.
Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing all nucleic acids in a sample, mNGS overcomes the narrow detection scope and slow turnaround of conventional tests, substantially ...
Tingting Fang, Feifei Yuan, Yu Chen, Na Li, Yao Zhang, Haixia Liu, Xingchen Liu, Qing Miao, Bijie Hu   +8 more
wiley   +1 more source

Evaluating the Sensitivity of Nontuberculous Mycobacterial Species Isolated from Water Samples to Conventional Antimycobacterial Drugs using E-Test Method

مجله دانشکده پزشکی اصفهان, 2012
Background: Nontuberculous mycobacteria were only known as environmental bacteria. However, they have recently been identified as important pathogens due to the increased prevalence of immunodeficiency diseases.
Ensieh Sarikhani, Bahram Nasr Isfahani, Nafiseh Sadat Hosseini, Tahmineh Narimani   +3 more
doaj  

Autofluorescence as a tool for structural analysis of biofilms formed by nonpigmented rapidly growing mycobacteria [PDF]

, 2013
The structure of biofilms formed by seven nonpigmented rapidly growing mycobacteria, including saprophytes and opportunistic species, was analyzed.
Estebana, Jaime, García, María Jesús García, García-Pedrazuela, María, Mahillo, Ignacio, Muñoz-Egea, María Carmen   +4 more
core   +2 more sources

Diagnostic and Clinical Value of Targeted Next‐Generation Sequencing for Pediatric Respiratory Infections in Northern China

The Clinical Respiratory Journal, Volume 20, Issue 4, April 2026.
A total of 1209 patients with suspected respiratory tract infections (RTIs) who underwent targeted next‐generation sequencing (tNGS) were screened at Qingdao Huangdao District People's Hospital, Qingdao, China, from April 1, 2023, to December 31, 2023. Of these, 940 patients were enrolled in the study.
Lixiang Wang, Xue Yang, Lexia Yang, Ke Yin, Hui Zhong   +4 more
wiley   +1 more source

Patients at risk of nontuberculous mycobacterial pulmonary disease who need testing evaluated using a modified Delphi process by European experts

ERJ Open Research
Background Identifying patients at risk of nontuberculous mycobacterial pulmonary disease (NTM-PD) is challenging. Delays in NTM-PD identification and management are associated with declining lung function and increased morbidity and mortality.
Michael R. Loebinger, Stefano Aliberti, Charles Haworth, Mateja Jankovic Makek, Christoph Lange, Natalie Lorent, Apostolos Papavasileiou, Eva Polverino, Gernot Rohde, Nicolas Veziris, Dirk Wagner, Jakko van Ingen   +11 more
doaj   +1 more source

American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel

Arthritis &Rheumatology, Volume 78, Issue 3, Page 509-522, March 2026.
Objective Vacuoles E1 enzyme X‐linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of inflammatory and hematologic manifestations, leading to increased morbidity and mortality.
Arsene Mekinian, Sophie Georgin‐Lavialle, Marcela A. Ferrada, Sinisa Savic, Matthew J. Koster, Olivier Kosmider, Thibault Comont, Mael Heiblig, Juan I. Arostegui, Annmarie Bosco, Rim Bourguiba, Katherine R. Calvo, Catherine Cargo, Chiara Cattaneo, François Chasset, Henrique Coelho, Corrado Campochiaro, Francesca Crisafulli, Stephanie Ducharme‐Benard, Raquel Faria, Franco Franceschini, Micol Frassi, Emma M. Groarke, Carmelo Gurnari, Yervand Hakobyan, Yvan Jamilloux, Ciprian Jurcut, Yohei Kirino, Austin Kulasekararaj, Hiroyoshi Kunimoto, Lauren M. Madigan, Heřman F. Mann, Chiara Marvisi, Marcin Milchert, Sara Morais, Katja Sockel, Francesco Muratore, Hideaki Nakajima, Mrinal M. Patnaik, Luísa Regadas, Marie Robin, Abraham Rutgers, Carlo Salvarani, Anthony M. Sammel, Joerg Seebach, Pierre Sujobert, Alessandro Tomelleri, Geoffrey Urbanski, Frédéric Vandergheynst, Romana Vieira, David S. Viswanatha, Ewa Więsik‐Szewczyk, Elisa Diral, Benjamin Terrier, Bhavisha A. Patel, Pierre Fenaux, Peter C. Grayson, David B. Beck, on behalf of the International VEXAS working group, and with endorsement of EuroBloodNet, the European Reference Network in Rare Hematological Diseases, Heřman Mann, Benjamin Terrier, François Chasset, Sophie Georgin Lavialle, Alessandro Tomelleri, Campochiaro Corrado, Carlo Salvarani, Francesca Crisafulli, Franco Franceschini, Micol Frassi, Yohei Kirino, Ewa Więsik‐Szewczyk, Marcin Milchert, Raquel Faria, Ciprian Jurcut, Joerg Seebach, Sinisa Savic, David Beck, Lauren Madigan, Matthew Koster, Patnaik Mrinal, Olivier Kosmider, Pierre Sujobert, Juan I. Arostegui, Catherine Cargo, David Viswanatha, Yervand Hagopian, Mael Heilblig, Pierre Fenaux, Thibault Comont, Bruno Alessandro, Chiara Cattaneo, Elisa Diral, Sara Morais, Austin Kulasekarara, Emma Groarke, Katherine Calvo, Patel Bhavisha, Anthony Sammel, Arsene Mekinian, Benjamin Terrier, Marie Robin, Sophie Georgin Lavialle, Katja Sockel, Yvan Jamilloux, Carmelo Gurnari, Henrique Coelho, Romana Vieira, Rim Bourguiba, Marcela Ferrada, Peter Grayson   +111 more
wiley   +1 more source

Characterizing non-tuberculous mycobacteria infection in bronchiectasis [PDF]

, 2016
Chronic airway infection is a key aspect of the pathogenesis of bronchiectasis. A growing interest has been raised on non-tuberculous mycobacteria (NTM) infection.
Alberto Pesci, Almerico Marruchella, Andrea Gori, Anna Stainer, Edoardo Simonetta, Finch, Francesco Blasi, Giulia Bonaiti, Giuseppe Lapadula, James Chalmers, Luigi Codecasa, Michael Loebinger, Okumura, Paola Faverio, Stefano Aliberti, Stefano Zucchetti   +15 more
core   +4 more sources

Solitary Pulmonary Mass due to Mycobacterium avium Infection in a Post‐Traumatic Lung: A Case Report

Respirology Case Reports, Volume 14, Issue 3, March 2026.
We report a case of solitary nodular Mycobacterium avium infection arising in a post‐traumatic lung. Chest CT showed a solid mass in the left lower lobe, and the diagnosis was established through thoracoscopic surgical resection. Graphical abstract image Figure 2C,D.
Takayuki Nakano, Shunsuke Yamada, Kozo Morimoto, Saya Hattori, Rino Arai, Mayumi Aoyama, Hideki Hashimoto, Tomoki Nakagawa, Hidenobu Shigemitsu, Ryota Masuda, Ichiro Kuwahira   +10 more
wiley   +1 more source

Nontuberculous Mycobacterial Tenosynovitis: A Case Report and Review of the Literature

Journal of Medical Ultrasound, 2015
Nontuberculous mycobacteria tenosynovitis is a rare clinical condition that commonly affects the hand and wrist. It is also a condition that is difficult to diagnose through clinical and roentgenological methods.
Liang-De Jiang, Hong-Jen Chiou, Hong-Dar Wu, Hsin-Kai Wang, Yee-Chen Lai, Yi-Hong Chou   +5 more
doaj   +1 more source