Results 41 to 50 of about 2,327 (198)
, 2016 Several 4-substituted 1,4-diazabicyclo[4.3.0]nonan-9-ones have been synthesized and tested in vivo on mouse passive avoidance test, to evaluate their nootropic activity.
Elisabetta Teodori (2209498) +9 more
core +1 more source
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality, Volume 38, Issue 7, July 2026.Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
INVESTIGATION OF NOOTROPIC DRUGS (PYRAMEM AND OROCETAM) FOR THEIR TERATOGENIC EFFECT
, 2017 The teratogenic effect of the nootropic drugs Pyramem and Orocetam on the skeleton and internal organs of rats was investigated. Pregnant Wistar rats were treated orally by 200 mg/kg b. m. Pyramem and 200 mg/kg b. m.
Alexandrov, N. +2 more
core +1 more source
Cognitive impairments in cerebrovascular disease: What is between health and dementia?
Неврология, нейропсихиатрия, психосоматика, 2015 The problem of cerebrovascular lesions takes on even greater significance with the higher prevalence of both acute and chronic forms of cerebrovascular diseases (CVD).
A. Yu. Emelin
doaj +1 more source
Borates in Biomedicine: A Retrospective Analysis
ChemMedChem, Volume 21, Issue 11, 15 June 2026.The graphical abstract displays the molecular structure of boric acid, an hormetic substance with pleiotropic bioactivity. Complementing previous studies describing the use of organoboron compounds as potent therapeutics for use in anticancer, antimicrobial, antiparasitic, and related other pharmaceutical uses, this study focuses on the emerging ...
Mario Pagliaro +3 more
wiley +1 more source
Interaction of vitamin D, homocystein and dental diseases
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 The 1,2,4-triazole nucleus is resistant to metabolism and is an important pharmacophore; it can increase solubility and improve the pharmacokinetic and pharmacodynamic profile of drugs.
Ye. O. Karpun +3 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Asiatic acid (AA) is a naturally occurring aglycone of ursane type pentacyclic triterpenoids. It is abundantly present in many edible and medicinal plants including Centella asiatica that is a reputed herb in many traditional medicine formulations for ...
Mohamed Fizur Nagoor Meeran +5 more
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Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Liberoid coffee (Coffea liberica group), comprising varieties of Liberica and Excelsa coffee types, is gaining attention for its unique chemical composition and sensory potential. However, its quality remains under‐optimized due to limited understanding of genotype‐specific traits and processing responses.
Noor Ariefandie Febrianto, Fan Zhu
wiley +1 more source
Anticonvulsant Properties of the Novel Nootropic Agent Nefiracetam in Seizure Models of Mice and Rats [PDF]
Epilepsia, 2005 Summary: Purpose:Nefiracetam (NEF) is a novel pyrrolidone‐type nootropic agent, and it has been reported to possess various pharmacologic effects as well as cognition‐enhancing effects. The present study focused on the anticonvulsant effect of NEF and its potential for antiepileptic therapy.Methods:The anticonvulsant properties of NEF were investigated
Yutaka, Kitano +5 more
openaire +2 more sources
Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Tommaso Braga +2 more
wiley +1 more source